4. Rosiglitazone, 12, is a type 2 diabetes drug that helps control the metabolism of carbohydrates...
2. N-bromosuccinimide is a synthetically diverse reagent. List four additional types of reactions, other than oxidation of a pyridines, in which NBS can be used. 3. Dihydropyrimidines can form with similar conditions and building blocks to the mechanism for the Hantzsch Ester following a Biginelli synthesis. Provide a mechanism for the formation of the following dihydropyrimidine. 4. Rosiglitazone, 12, is a type-2 diabetes drug that helps control the metabolism of carbohydrates and fatty acids. Provide a mechanism for the conversion...
2. N-bromosuccinimide is a synthetically diverse reagent. List four additional types of reactions, other than oxidation of a pyridines, in which NBS can be used. 3. Dihydropyrimidines can form with similar conditions and building blocks to the mechanism for the Hantzsch Ester following a Biginelli synthesis. Provide a mechanism for the formation of the following dihydropyrimidine. 4. Rosiglitazone, 12, is a type-2 diabetes drug that helps control the metabolism of carbohydrates and fatty acids. Provide a mechanism for the conversion...
explaim the mechanisms amd toxological effects if type 1 diabetes in this article Exposure to arsenic in drinking water is associated with increased prevalence of diabetes. We previously reported an association of diabetes and urinary concentration of dimethylarsinite (DMAS"), a toxic product of arsenic methylation by arsenic (+ 3 oxidation state) methyltransferase (AS3MT). Here we examine associations between AS3MT polymorphism, arsenic metabolism and diabetes. Fasting blood glucose, oral glucose tolerance and self-reported diagnoses were used to identify diabetic individuals. Inorganic...