Example for SN1 reaction hence gives racemic mixture.
Rearrangement of carbocation intermediate occurs to get more stable benzylic cation.
Activity 11 1. For the following reaction draw the reaction mechanism and the product: ОMe Br...
1. For the following reaction draw the reaction mechanism and the product: OME TSO ETOH cold major product NMR lacks peaks in the 4-6 ppm range Et 2. Draw the product for the following reaction: NaOH Но Product IR contains a broad stretch at 3300 cm (no other interesting stretches) 3. Indicate all the reagents that lead to the following oxidative cleavage product:
Draw the mechanism and major product for the following E2 reactions ОMe ОМe Br Br
1. Draw the major organic product of the following reaction. Include stereochemistry if appropriate NaOEt aqueous HC EtO OEt EtOH for neutralization of the reaction mixture 2. Draw the major organic product of the following reaction. NMR spectra are provided for this product 200 180 160 140 120 100 80 60 40 NaOH CH3 ethanol heat 10 9 8 6 5 4. 2 1
Draw a detailed mechanism for the following transformation 1. Br. Br HBr HO 2. What are the major product (s) formed in the following substitution reaction? Draw as Fisher projections CH;CH2ОH CH-CHз Нас— вr CH2CH2CH3 Draw the mechanism for the following reaction. 3. HO Br Draw the major organic product(s) produced in the following reaction as Fischer projection. 4. CHз ОСHЗ Н NaN3 Н. -CH3 Н- Br DMSO CH3 Draw the mechanism for the following reaction to demonstrate how the...
26) Predict the major product for the following reaction and draw the full mechanism for product formation (Hint: Aldol Condensation Reaction) 6 pts NaOH/H2O Heat Н. Bonus: Provide a step wise synthesis for the following conversions? 6 Pts (Multi step) wie Br A) OH OH NH2 B) OH C)
26) Predict the major product for the following reaction and draw the full mechanism for product formation (Hint: Aldol Condensation Reaction) pts NaOH/H2O Heat H Bonus: Provide a step wise synthesis for the following conversions? 6 Pts (Multi step) Br A) OH NH OH B ) OH
Draw the mechanism that explains the product of the following
reaction
11. (10 points) Draw the mechanism that explains the product of the following reaction: Brz H.O HO, Me Br + ent.
What is the major product of the following reaction?
Br NaOCH3 HOCH3 Hmmy HH OMe Racemic Mixture B H Et ОMe
Predict the major organic product of the following reaction and complete its mechanism below. 1) NaOEt/EtOH 2) CH3CH2CH2Br 3) dilute NaOH/heat 4) H30* 5) heat Complete the curved-arrow mechanism for the scheme below by adding any missing atoms, bonds, charges, nonbonding electrons, and curved arrows. :O O: :Br. CH3CH2OH Do not show curved arrows for this step. Added acid Dilute HH NaOH and heat hydrolyzes the ester. O: Na Br - H20, Na* O: 100-150 °C O:
2. For the reaction below: a. Predict the most stable product(s) and draw the mechanism Br OK b. Redraw the product/s) below and label all the non-equivalent carbons. How many sonals would you expect to see in the C NMR of the product? Predict the chemical shifts of each carbon below. c. Redraw the product(s) below and label all the non-equivalent hydrogens. How many signals would you expect to see in the 'H NMR of the product? Predict the chemical...