2. What is the major product of the following reaction sequence? 1. H2, Pd/CaCO3, quinoline 2a. Hg(OAc)2, H2O 2b. NaBH4, NaOH A) OH B) OH * HO D) HO, E) 1
g. Ph-C(O)-NH2 4 NaOH Br2 h. (HC)2CH-C(CHa)2 -> HO N(CH3)3 i. Ph-N2, CI- + CuCN --> H30* (cat) Na/ETOH j. cyclohexanone+ H2NOH Pd(OAc)2 (1 mole%) k. Ph-I + 4-O2N-C&H4-HC=CH2 Cul/Pd(PPH3)4) L. HO-CH2-CH2-CC-H +1-CH=CH-(CH2)4-CH3
8. Is the following sequence of steps an appropriate synthesis for ibuprofen? Yes or No CHCH CH,CH3 HOCH CH OH (CH)2CHCc на AIClh CH CH3 Br -CHCH HOOC-CHCH3 HOOC-CHCH3 1.Mg, ether NES H2/Pd 3. Ho*
8. Is the following sequence of steps an appropriate synthesis for ibuprofen? Yes or No CHCH CH,CH3 HOCH CH OH (CH)2CHCc на AIClh CH CH3 Br -CHCH HOOC-CHCH3 HOOC-CHCH3 1.Mg, ether NES H2/Pd 3. Ho*
please help
1. (4 pts) Draw the major product for each series of reactions. a. BzH6, diglyme b. NaOH, H2O2 a: MSCI, py c. MSCI, py d. NaCN, DMSO a. HBr, peroxides b. KOC(CH3)3, DMSO c. Bra, CH2Cl2 a. HBr, CH,CI2 b. KOC(CH3)3 c. HBr, peroxides d. NaCEC-CH3 Hz, Pd/CaCO3 CH3 CH2CH2OH O Pb(OAC)
Problem #2 Complete the following reactions: H2(g) CH3 Naº, NH3(1) Pt Наса H2(g) Pd on CaCO3 PbO2
Problem #2 Complete the following reactions: H (9) CH3 Naº, NH3(0) H₂C H2(g) Pd on CaCo3 PbO2
Draw the Products of the following reactions
Pd(OAc)2, PPh 40 Cs2CO3 B(OH)2 NH2 1) Ph OVH NaHB(OAc)3 to DCC, CH Ch Ο ΟΗ Heat HNCNH OH Me
(1) Hg(OAc)2, H2O (2) NaBH4 NO2 H2, Pd/C KMnO4
Practice Worksheer 8: Alkynes 4. Draw the major product for each transformation. Draw the major regioisomer and sterosome where appropriate. CI, CHCI HgSO4, H,SO a. B He, diglyme b, HD, NaOH H2 (excess), Pd/C CHE Hz (excess), Pd/CaCO3 quinoline, Pb(OAC) CH₃ Na”, NH3(1), -196 °C Page 3 of 4
Give the organic products of the reactions. INCLUDE
STEREOCHEMISTRY & REGIOSPECIFICITY.
CH3 CH,CH2CCH2C CH 2 HBr CH3 Pd/BaSO4 C C H2 Pt + 2D2 CH3(CH2)3C CH Na Ph-C C-Ph NH3 1) (CH3)C-O NANH 2) H2O CH,C CH