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Q: discuss the cellular movement of K+ in acidosis as compared to alkalosis

Q: discuss the cellular movement of K+ in acidosis as compared to alkalosis

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  • Potassium is critical For many biochemical cellular reactions .
  • The body maintains potassium concentration primarly through the action of kidneys .
  • Potassium is freely filtered by the glomerulus .it is actively reabsorbed in a proximal tubules .
  • The potassium concentration can be affected at the cellular level by a number of factors .
  • The pH of the extracellular environment is one of the major influence on potassium serum concentration .
  • Acidic conditions promote the cellular uptake of H+ to maintain homeostasis .For each H+ taken up by the cells , a K+ is moved extracellularly to preserve electroneutrally .
  • Alkalosis has the opposite effect , promoting cellular uptake of K+ in exchange for H+ .
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