Question

Outline the sequence of events in an antibody related immune reaction and correlate these events with the clinical presentation of such a reaction

Answer 1

Immune response;

mm Immune gesponse:- - Immune response is what the immune system does when confronted by an antigen » Immune response is an elaborate isterplay between antigen, non-specifie defenses, B and a lymphocytes. *) process involves direct contact (Cells, moleules bind to acceptors on cell surface, and cytokines (messenger molecules) that also bind to receptors on all surdaus.

Types of immune response;

UU classification & Immune responsesar » Humoral >> cell mediated type, & may work together may work is opposite way. >> on тря bе mоѕ acife Than oThя.

Humoral and cell mediated immunity;

Immune response ons Humoral cell mediated Active against most I protect against Entia cellular Bactericu fungus, viruses, pathogens Bacterial Protections participates is Type 1,2,3 Hypersensitivity T-cells mediated reactions Hypersensitivity Auto immure Disordeus autoimmure disordes.

Anybody mediated immune response;

Humoral Immune Responsel. Produce antibodies Bulls- plasma ells. - Antiger presented to Inmurscompetert. acell proussed secretion of antibodies

Sequence of events in antibody mediated immune response;

Three stagess. Istage » estry & artiger, its distribution and feete in the tissue and its contact with appropriate Inmurocompetesk cellp. 2 stage - secretion & antigen by cells and The control of the antibody forming process 3 stage & secretion of antibody its distribution is issue and body fluid and manifestation its Elect.

Phase of antibody production;

pattern of antibody Productions. & A lag phose » * log phase + gaiso y antibody levels a plateau phase » & phase of declire sent

Inactivated Bell microbe antibody - Dactivated Bell Proliferation and differentiation

Clinical presentation with immune response;

• It involves in the prevention of recurrence of virus infection.
• And also involved in hypersensitivity reaction( 1,2 and 3 ).
• Involved in autoimmune disease.
• 
  Anti boobies as Diagnostic and Therapeutic agentor Based on specifity and affinity of antibodies Both applications require lenge quantities of Identical antibodies. » monoclonal antibodies are produced using oma cell line, » Hybridoma cell cire derived from single antibody producing cell fused with myeloma