Question

according to the chemiosmotic theory, the synthesis of 1 mole of ATP is coupled to the movement of 4 moles of H+ ions from the low-pH side of the membrane to the high-pH side. (a) derive an expression for delta G for the movement of 4H+. (b) calculate the change in pH across the membrane required to synthesize one mole ATP from ADP and O under standard-state conditions and 25C . DeltaGknot=31.4kJ and for the synthesis of 1 mole of ATP.

Answer 1

@ In cell, the movement of ynt from a region of higher concentration outside the membrane hoone of lower concentrations ingide will lead to produelion of one Atp molecule. The AG required for the hydrolysis of one ATP molecule in the cell, under optimum conditions is AG = RT ln ( 22 ) Where Redakconstant T= Temperature * 4G = /2.48 kglmal) (nu) = (2.48 kg Imol) (1.38) = 3.422 kJ/mol LAG = 3.422 k5lmod]

Given ArG'= 31.4 kJ When one molecule of Arp is synthesized from the app and pi under the optimum conditions, there will be a consumption of 3H+ for the Synthesis. : ; --the pH of the system will incrcase as the H+ concentration is decreased.