Question

Sally is a 43-year-old mother of two who has gained 50 pounds over the past 5 years. She is 64 inches tall and weighs 180 pounds with a BMI of 31. Her waist circumference is 37 inches. She acknowledges that she is not as physically active as she would like to be. She also notes how recent stresses in her life have affected her sleep and seem to have triggered her appetite for sweets and comfort foods. Sally’s father recently died from complications of type 2 diabetes, and her mother and sisters are overweight. Sally says she is very motivated to “not get diabetes” and is disturbed that her recent physical exam revealed mildly elevated blood pressure, glucose, and cholesterol levels.

Sally has been told that she most likely has gained weight from having a higher percentage of white adipose tissue, due to inefficient uncoupling proteins. What would you tell her?

a. White adipose tissue releases heat and burns fat, so that is not a reason to gain weight

b. It is her lack of sleep that is increasing her white adipose tissue; better sleep would decrease white

     adipose tissue

c. Exercise would be beneficial to help produce a “browning” effect on white adipose tissue by producing

     fat cells known as “brite adipocytes”, therefore decreasing white adipose tissue percentage.

d. Drinking large amounts of coffee would decrease white adipose tissue percentage.

Answer 1

Option:C

Exercise would be beneficial to help produce a browning effect on white adipose tissue by producing fat cells known as Brite adiposites therefore decreases white adipose tissue percentage.

Physical exercise contribute white adipose tissue browning which increases the energy expenditure.

Brite adipocytes are used for treating obesity and diabetes