2. (12 pts) Reactions Give the reagents or products to the following systems. If a reaction...
Chem 6A Homework #8 (28 pts) Due: 12/2/19 in class Give the organic product(s) of the following reactions Name Write your answers on this sheet. 1) CH3CH Mg CH3CH2CH2CI 2) H,о 1)LIAIH 2) н,б осн, н 1) ether Acetone CH3CH2CH2LI + 2) н,о* Hас Он 1) NaBH 2) н,о' BrMgсHCH,CHз CH2CH3 2) Н,о он Он РСС он PBr он о о но TsCl KCN CH3CH2OH
heat НО Н ETOH 1. SOCI2 НО н 2. Heat, ETOH 1. TsCl Но н 2. CH3ОK, CH,он
) (30 Pts) Provide the structure(s) of the expected major organic product(s). Unless mentioned otherwise, you can assume that all reagents are present in one mole. Show stereochemistry where needed and write NR if there is no reaction. о ОН E) NaOH, H2O АллОН ОН F) СН2ОНО. ОСН3 H НО H2O, HNO3, 60 °C Н. ОН CH2OH H
Give the product(s) of reaction of hexanal with each of the following reagents. 2. (0) носн,сн,он, н (b) 1. LIAIH, 2. H,0* (e) NH,он, н" (d) NH,NH2, KOH, heat (e) (CH),СHCH,CH— P(C, Нә» , н" (g) Ag, NH, H,O (h) CrOs, H,SO H,0 () 1. KCN, 2. H,SO MCPBA Give the product(s) of reaction of hexanal with each of the following reagents. 2. (0) носн,сн,он, н (b) 1. LIAIH, 2. H,0* (e) NH,он, н" (d) NH,NH2, KOH, heat (e) (CH),СHCH,CH—...
For each of the following questions, provide the missing reagents (that can be purchased) and conditions or predict the MAJOR product. Indicate stereochemistry and identify a racemic mixture if applicable. If no reaction occurs, write out "no reaction." . a. d. Ag,O/NH,OH "ОН e. 1) CH (CH,),Br/ 2 Li 2) HCI f но но но. (:) g. н NH NH
Give the organic products, with the CORRECT REGIOCHEMISTRY AND STEREOCHEMISTRY, when appropriate. !!! CH3 -C CH-CH + HI Нас CH2OOCH C CH-CH2CH3 +HBr Pd + D2 CH3 Но C CH- CH2CH3 Н-о + Нас 1) (BH3)2, THF 2) H-0,. ОН" Cн, Н.о" CH3CO;H CH3 CHCI/ KOH cCH Hас H +Cl2
8. Predict the major organic products of each of the following reaction conditions (20 points) 1) LiAIH diethylether н 4 2) Н-о Н.о KOH CrO,, H,SO,, H,О он acetone (co-solvent) 1) CH3MgBr, diethylether 2) Н-о 9. Show how you could synthesize the targeted products from the starting epoxides. Show all reagents and reaction conditions in the boxes above the reaction arrows Но Hас ОСHЗ но O
15. (3 pts each) Give the product(s) for the following reactions, and name all reactants and products. CH, он ОН н,с + H3c— сн - сн 3 Нас NH2 он + о н Н H-с-с-о-н Но -P -ОН н Н ОН
Ch 16.1 Give the major product(s) or the following reaction ao,a OH N ? OH io OH H There is no reaction under these conditions or the correct product is not listed here Gve the major product(s) of the following reaction COCH OH N H OH 0 OH H There is no reaction under these conditions or the correct product is not listed here. В 1) BAIH (-Bu), (-78°C) (0.5 moles) 2) ное ? оо н ОН ОН OCH, OH...
(4 pts 2 pts EC) Predict the products for the following reactions. Pay attention to stereochemistry 2. where appropriate HO SOCI2 а. dioxane 1) TsC pyridine Он b. 2) LIAIH4 1) TsCl pyridine но° C. 2) Nal OH РСС d. CH2CI2 он NaOCI но, acetic acid он NaOCI Он ТЕMPO