Show two synthe sis routes of the following product using a Wittig reaction (10 points)
2- Show the how each alkene can be synthesized by a Wittig reaction including mechanism. (There are two routes to each). Plus show how to synthesize the corresponding ylides.
Determine the missing reactant for the two routes to create the following alkene by a Wittig reaction. Route 1: PPh3 view structure Ph3P Route 2: view structure Part 2 out of 2 Which route is preferred? 0 Neither route is preferred over the other Route 1 Route 2
Practice: Devise a synthesis of the following molecule using the Wittig reaction. Product alkene trigaostoitudad
5. Show how you could synthesize the following. (16 pts) A Using the Wittig reaction y vang Ho wang reason Mo + Phypoger 8 ОН Hint: Use the appropriate aldehyde or ketone, and a Grignard Reagent 6. Write the mechanism for the following reaction. (8 points) OH 1. emger 2. H₂O*
The Wittig Reaction 1. Complete the following reactions by filling in the blanks with the correct structures. (15 pts) NaOH PPhy COOH The scheme above is the reaction you were supposed to perform today. Answer the following question pertaining to the experiment (page 43-44). (a) The first reaction was run in acetone and the product filtered (we can instead, just remove the acetone on the rotary evaporator). What is the product? (5 pts) (b) The product obtained in part 1...
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Ochem 2
Draw the organic product of the following Wittig reaction.
11. There are two ways to utilize the Wittig reaction to prepare
the following. Draw the starting materials for each possible
method.
11. There are two ways to utilize the Wittig reaction to prepare the following. Draw the starting materials for each possible method. method 1 method 2
Show how the Wittig reaction might be used to prepare the following alkene. Draw the alkyl bromide and the carbonyl compound that you would Do not separate two structures with a + sign.
Wittig Reaction Lab: Provide the appropriate Wittig product(s) formed from the following starting materials [assume the addition of aqueous sodium hydroxide in order to create the reactive ylide intermediate]. Clearly indicate any chiral centers and E/Z isomerism: a) o-methylbenzaldehyde, triphenylphosphine, and (R)-1-bromo-2,3-dimethylbutane b) (S)-1-chloro-3-ethylhexane, triphenylphosphine, and cyclopentanone
Stilbene is synthesized using the Wittig reaction. What is the starting aldehyde and ylide compound in the reaction? Show the mechanism of the ylide formation and then show the mechanism, using the same ylide and aldehyde, to create benzil.