4. (12 marks) For each of the following reactions, predict the MAJOR product with correct stereochemistry.
4. (12 marks) For each of the following reactions, predict the MAJOR product with correct stereochemistry....
4. (12 marks) For each of the following reactions, predict the MAJOR product with correct stereochemistry (a) NaSCH: CH3SH Se(CH3)2 DMF NaOH SH hint:product has a Satom in a ring (d) OTS ethanol
(12 marks) For each of the following reactions, predict the MAJOR product with corre stereochemistry. (e) NACN acetone (f) CH3 -н 1 eq. NaNa DMSO -H OH н- CHз
4 (12 marks) For each of the following reactions, predict the MAJOR product with correct stereochemistry NaSCH: CH,SH Se(CH3)2, NaOH NaOH hint product basa Satominating OTS ethanol
4 (12 marks) For each of the following reactions, predict the MAJOR product with correct stereochemistry NaSCH: CH,SH Se(CH3)2, NaOH NaOH hint product basa Satominating OTS ethanol
1. Predict the major substitution product(s) for the following reactions. Include stereochemistry if appropriate. You may assume an aqueous workup is performed after each reaction. 1. Nah, DMF ТОН 2. Mel BrMg-Ph KCN 16 { ad ton ot MeOH HD Na Br Me DMSO EtOH Br ~ Br DMSO * Me OH LNH2 M HO Me-S (1 equiv) Me DMF
For the following reactions, predict the MAJOR product(s). If a pair of enantiomers is expected, draw both enantiomers. NaSH Cis-1-bromo-3-methylcyclohexane acetone OTs 1. NaI/acetone 2. NaCN/DMF CH3 NaCN H,с. Br CH3 Бшн.
use the above guidelines to predict the major organic product of the following reactions. JPB 2020 8.18 Points -Exception-substitution can occur with weak bases (CN, N3, SH, SR) -Exception-3° alkyl halides undergo substitution (solvolysis) with alcohols. 3. Use the above guidelines to predict the major organic product of the following reactions. (5) CIK* -OC(CH3)3 CH3 C. CH3CH2-C-CH3 + CH,OH — Br + CH20- CH2OH n o -Br + NACN + NaCN - DMSO DMSO
16. Give the major product that you would expect to be formed in each of the following reactions. If you think there is no reaction write NR after the arrow. In each case give the mechanism (SN1, SN2, E1 or E2) by which the product is formed. Also indicate the correct stereochemistry when applicable. Both product and the mechanism should be correct to get credit. No partial credit. Nal -BuOK Acetone t-Buo NaSH DMF Br, H NaOMe DMSO MeOH,rt t-BuOH...
Predict the product(s), both major and minor, of the following reactions. Indicate stereochemistry where appropriate. Br. H Nang g DMF OH H2PO4 OMS KOC(CH3)3 HOC(CH3)3
1) Predict the outcome of the following 4 reactions 1) Predict the outcome of the following 4 reactions MeOH Ph reflux XPh MeΝΟ, reflux Y Br MeNO2 MeSNa DMSO Ph reflux Br 2) For the following 5 molecules predict whether an E2 elimination would be possible for the DRAWN conformation. Do not attempt to rotate around any bonds, judge based on the conformation shown. If yes, show the product. Br Ph BCH Meph Me Y y o tadi men 3)...