1. Predict the major substitution product(s) for the following reactions. Include stereochemistry if appropriate. You may...
Predict yhe Major product of each reaction and include stereochemistry where appropriate. You may assume an aqueous workup after each transformation. thanks a bunch in advance for helping transformation. NaSH MeOH 3 NaOEt CH,Br (1 equiv) Me-MgBr Mous DMF Nao
1) Predict the outcome of the following 4 reactions 1) Predict the outcome of the following 4 reactions MeOH Ph reflux XPh MeΝΟ, reflux Y Br MeNO2 MeSNa DMSO Ph reflux Br 2) For the following 5 molecules predict whether an E2 elimination would be possible for the DRAWN conformation. Do not attempt to rotate around any bonds, judge based on the conformation shown. If yes, show the product. Br Ph BCH Meph Me Y y o tadi men 3)...
In the substitution reactions below, draw the major product in the box provided and indicate in the small box whether the reaction is SN1, SN2, or neither. Be sure to show all stereochemistry. If more than one enantiomer is produced, write "+Enant" in the box with the product. [10] Product SN1/SN2/Neither NaCN Br DMSO NaOEt EtOH Br NaOMe MeOH NaOH Expensive Acetonitrile CH,Br DMF Nat
4. (12 marks) For each of the following reactions, predict the MAJOR product with correct stereochemistry. 4. (12 marks) For each of the following reactions, predict the MAJOR product with correct stereochemistry. NaSCH3 CH3SH (b) - Se(CH3)2 DMF SelfH3)2, con "ayam HD M NaOH sH - hint: product has a S atom in a ring (d) ethanol fone come NaCN acetone CH3 ci+H 1 eq. NaN3 DMSO HOH CH3
Predict the product(s), both major and minor, of the following reactions. Indicate stereochemistry where appropriate. MeOH/heat а тюх меонтоа, а. NaOEt EtOH HCI
Of the following equations predict the product of the reactions. Include stereochemistry in cases where more than one product is formed . Circle the major product of the reaction 0 CH2CH3 Br CH13 0, HI (2 equivalents Он (1) NaH CH3CH2 Choosing reagents and reaction conditions of your choice, propose a two-step transformation of the given substrate Br Br KOCICH3)s (2 equiv)
1. Determine whether the following reactions go through SN or SNP and write the products, with stereochemistry as applicable. BrNHz NaOEt Nal OMS KCN CI DMSO Br HO NaSH DMSO Tso CH3 Nal Acetone CH3 2. The following reactions each undergo SNmechanisms. For each explain why you would predict the substitution products to come from an SN2mechanism and fill in the product. If stereochemistry is given in the reactants, give the correct stereochemistry in the products. Cl + Z Na...
1. Predict the product(s) of the following SN2 reactions and include stereochemistry where necessary. Br КОН NaOCH DMSO
Predict the Major product(s) for the following reactions and draw their corresponding arrow-pushing mechanisms. If there is no reaction write NR. (21 points total) detailed Show the correct stereochemistry when needed KOH THF substitution Cl Mechanism: MeOH substitution Mechanism: CI t-BuOK, DMF heat elimination Mechanism:
Predict the product(s), both major and minor, of the following reactions. Indicate stereochemistry where appropriate. Br. H Nang g DMF OH H2PO4 OMS KOC(CH3)3 HOC(CH3)3