Question

• Define dementia of Alzheimer type (DAT) and describe the pathophysiology, clinical manifestations, evaluation and treatment.

Answer 1

ODementia of Alzheimer type is a progressive disease in which Patal neurodegeneration is seen 2t is mos Jeen in eldenly in which they Pogresively loss their and detosiošadion is memory casoy out dialy activities geen in ability -to Pathophysiolagy Degeneration of lage Pyramidi al cells hich ane present in cerebral cortex and aleng with cholinergic neurons and subcor tical structuoresand neurof b rillay tangles and senile plagues through out the brain Clinical manifestations Confusion, delusion, forgetfulness, aggesion, iritability, xestless ness, agitation, ang toneliness, mood jumbled speech, loss of appedite, paanoia O he Atro fy of corfical Ssings a depreni on, halucination symptoms of DAT Evaluation Neusological etaminations, signs Sy mptoms evaluation, physical examination Treatment: -No cune Medication such as cognition- cnhancing given to improve ymptomp a1e