Question

complete the following information. If needed, review and/or research nucleophilic substitution reactions in your lecture textbook. 1. SN2 a. Name = b. How many molecules involved in slow step? c. How many steps involved in mechanism? d. List what occurs in the step(s) e. When do you have to worry about chirality? f. What type of reactants undergo SN2? g. Secondary reactants undergo SN1 & SN2. If the nucleophile is negatively charged, what solvent (polar protic or polar aprotic) will support SN22 h. Secondary reactants undergo SN1 & SN2. If the incoming nucleophile is a weaker base than the leaving group, what will occur?

Answer 1

Ariswers. 01. SN2: : (a). substitietion Nucleophillie Bimolecular. (6). 2- moleecles. (That's why the name is have Bimolecular). (e). Single step. i svolved. (d). (i) Nueleophile approches from back side, (ie). a Transition State produced. Bu Leaving group left the molecule. * all the things stakes place in a single steps e) I, the compound is chiral, then inverse of configuration will be obtained in produet. Because, a in sN 2 mechanism, inversion of configuration takes place. (f). Carbon centre with less number of -R group ataened iceos porondly contain : Compound 1°, ove 2º carbon centre, undergo SNQ, Heactioni In SN2reaction backsidi attack takes place, hence, back side must be less - Sterically crowded. (9). If the nucleophile is onegatively charged, then polar apreotic solvent will support sN 2 because a sthis dp rotic solvent stabilize cation but keep free anions which can undergo SN2 Meaction. Ch) stow ngen base Thom Keaving grotep com release the leaving group. If weaner base them leaving group is used then sN2 reaction con cannot takes place. .