Question

0 1. The following reaction was recently reported along with a proposed catalytic cycle below: co Pd(PPhg) (1 mol %) CsOAC (1.0 equiv) THF, 60 °C, 16 h Na 32 examples up to 99% yields , co PdLI NHR ACOH CO2 COAC NHRC

what transformation needs to occur to convert the Pd-catalyst added, Pd(PPh3)4, to the active catalyst A? what number(s) could n equal in Pd0Ln?

Answer 1

Sol Given data Pd (pph3) 4 (1 mol/ CSOA (1.0 equiva) -NH COR THE 60°C, 16h. Catalytic Cycle pa Pal Pd La I -WHR 5 ) کے "Pd Lo I ACOH HR Co Oac

What transformation needs to occur to Pd-catalyst added , Pd (PPh3) 4, to the Catalyst A Convert the active oxidative addition Deaction, we need to add Pd (PPhy). When it add in the Compound it Oxidise into pd at Which is most Stable State of Pd. The number Could be n=t. In Pd Ln, not more than 4. Otherwise bulky group starts repilling to each other .