name the mechanistic step that converts E to D 1. The following reaction was recently reported...
name the mechanistic step that converts D to A 1. The following reaction was recently reported along with a proposed catalytic cycle below: CO Pd(PPhal. (1 mol %) CsOAC (1.0 equiv.) NH (co. THF, 60 °C, 16 h - 32 examples up to 99% yields Pd'LL NHR DOLO CO CsOAC "polli NHRC
name the mechanistic step that converts B to C 1. The following reaction was recently reported along with a proposed catalytic cycle below: O CO Pd(PPh3)le (1 mol %) CSOAC (1.0 equiv + THF, 60 °C, 16 h NH (Co. R 32 examples up to 99% yields PdL A NHR Co2 L Pg . Pd' L CO -Pd'L2 O NHR E R в D Rv Csl ACOH со CO2 СВОАС NHR C zac
1. The following reaction was recently reported along with a proposed catalytic cycle below! co Pd(PPhals (1 mol %) CSOAC (1.0 equiv) Y O NH CÓ THF, 60 °C, 16 h. No Ž-C 32 examples up to 99% yields Pd NHR Csi ACOM PA COAC NHRC a. Name the mechanistic step that converts A to B -
what is the role of CsOAc? 0 1. The following reaction was recently reported along with a proposed catalytic cycle below: co Pd(PPhg) (1 mol %) CsOAC (1.0 equiv) THF, 60 °C, 16 h Na 32 examples up to 99% yields , co PdLI NHR ACOH CO2 COAC NHRC
what transformation needs to occur to convert the Pd-catalyst added, Pd(PPh3)4, to the active catalyst A? what number(s) could n equal in Pd0Ln? 0 1. The following reaction was recently reported along with a proposed catalytic cycle below: co Pd(PPhg) (1 mol %) CsOAC (1.0 equiv) THF, 60 °C, 16 h Na 32 examples up to 99% yields , co PdLI NHR ACOH CO2 COAC NHRC
All of the following questions are in relation to the following journal article which is available on Moodle: Parr CL, Magnus MC, Karlstad O, Holvik K, Lund-Blix NA, Jaugen M, et al. Vitamin A and D intake in pregnancy, infant supplementation and asthma development: the Norwegian Mother and Child Cohort. Am J Clin Nutr 2018:107:789-798 QUESTIONS: 1. State one hypothesis the author's proposed in the manuscript. 2. There is previous research that shows that adequate Vitamin A intake is required...
1. According to the paper, what does lactate dehydrogenase (LDH) do and what does it allow to happen within the myofiber? (5 points) 2. According to the paper, what is the major disadvantage of relying on glycolysis during high-intensity exercise? (5 points) 3. Using Figure 1 in the paper, briefly describe the different sources of ATP production at 50% versus 90% AND explain whether you believe this depiction of ATP production applies to a Type IIX myofiber in a human....