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Anonymous 2. Malignant Disorders of White Blood Cells • Malignant Disorders of White Blood Cells a. How do the various types
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  1. In leukemia, the immature white blood cells flood the blood stream and marrow. Lymphoma usually starts in the lymph nodes and leads to the proliferation of lymphoblasts. Myelomas are plasma cell tumors and lead to aggregates in bone marrow.
  2. White blood cells are formed in the bone marrow. During malignant transformation of cells, immature WBCs are produced in excess and take up all the space in the bone marrow ( the place they originate from). This, bone marrow involvement is more or less inevitable.
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