Question

Gastric juice is made up of substances secreted from parietal cells, chief cells, and mucous-secreting cells. The cells secrete HCI, proteolytic enzyme zymogens, mucin, and intrinsic factor. The pH of gastric juice is acidic, between 1-3. If the pH of gastric juice is 1.7, what is the amount of energy (AG) required for the transport of hydrogen ions from a cell (internal pH of 7.4) into the stomach lumen? Assume that the potential difference across the membrane separating the cell and the interior of the stomach is -70.0 mV (inside of cells negative relative to the lumen of the stomach). Assume that the temperature is 37°C. The Faraday constant is 96.5 kJ. V-1 mol and the gas constant is 8.314x 10-3 kJ. mol-. K1 Express your answer in kJ/mol. Number kJ/mol

Answer 1

Ansyue Given that, PH ol gastric juice 7 inteRnal pH ot (eu is Eo s-o orio Aheve e, 14 Concentration al ftnsidelo e 001995H Concentation al H ouside: lo 3-93 162 (tJauside NOL, keg (Hinside 2.98 (o8 leg O 01995 leen= 2 l0 The amant of Energj iS Cal culated by AGI-RTIMe -O A Clesdig to given n formation R baslanstun 7 Tnemperatuve in teium 37 31015 k eEquitibiun (nstaut

Nov, Substitte -these lalues ih 2quatiun (9alu X to3310 15) nl2xo 1-32 3h AG A 33.3H S/hro Now AGL nFEo ACcosdig to tue guen nfAmaton Favaday Constut 96.5 k3.Vmo F 17 3.31 lo3 te Jmor - R Gnasonstaht Co 0 3 v Eo (2 Naw Substitte tue lealues i x96-5 x 1-0 103 AGL =6.75 kmol Therefre, The amovnt helgy (A) vequved is Caltuleted

3 A A2tA2 6.75 t33.H Ho.59 kJ/mol Thevefe, The anaunet ofhegy As vequved for the tvansport hydvogen fons fron a cell into tue Stomach lumen isHosa /mo