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Aim of assessment The purpose for this case shudy essay is to enable students to produce an assignment using evidence-based i
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Type 1 diabetes is an autoimmune disease that causes the insulin-producing beta cells in the pancreas to be destroyed, preventing the body from being able to produce enough insulin to adequately regulate blood glucose levels.

Type 1 diabetes is caused by a fault in the body’s immune response in which the immune system mistakenly targets and kills beta cells, the cells in the pancreas responsible for producing insulin.

As more insulin-producing cells in the pancreas are killed off, the body can no longer control its blood glucose levels and the symptoms of diabetes begin to appear.

What causes the initial fault in the immune system is yet to be discovered, however, research suggests that the condition results from a combination of genetic predisposition with an environmental trigger.

Symptoms may include:

  • Above average thirst
  • Tiredness during the day
  • Needing to pee regularly
  • Unexplained weight loss
  • Genital itchiness

Diabetic ketoacidosis (DKA) is a dangerous complication faced by people with diabetes which happens when the body starts running out of insulin.

DKA is most commonly associated with type 1 diabetes.

Clinical Manifestations:

  • Vomiting
  • Dehydration
  • An unusual smell on the breath –sometimes compared to the smell of pear drops
  • Deep laboured breathing (called Kussmaul breathing) or hyperventilation
  • Rapid heartbeat
  • Confusion and disorientation

Management:

Treatment of diabetic ketoacidosis involves administering intravenous fluids to correct dehydration and to replace any salts that may be lost from the body during ketoacidosis through passing excessive quantities of urine.

Insulin is also required to instantly suppress the ketone bodies that the body manufactures.

If an infection has been the underlying causes of DKA, you will be given a sick day plan to help you take the right amount of insulin. Close observation of the patient to quickly identify and prevent complications is essential until your his levels have stabilised.

Medications:

  • Fluid replacement: fluids either by mouth or through a vein (intravenously) until the stage of normal hydration. The fluids will replace those you've lost through excessive urination, as well as help dilute the excess sugar in your blood.
  • Electrolyte replacement. Electrolytes are minerals in your blood that carry an electric charge, such as sodium, potassium and chloride. The absence of insulin can lower the level of several electrolytes in your blood. The electrolytes administered through a vein to help keep heart, muscles and nerve cells functioning normally.
  • Insulin therapy. Insulin reverses the processes that cause diabetic ketoacidosis. In addition to fluids and electrolytes, administer insulin therapy usually through a vein. When blood sugar level falls to about 200 mg/dL (11.1 mmol/L) and blood is no longer acidic, it may be able to stop intravenous insulin therapy and resume normal subcutaneous insulin therapy.
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