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Mrs. Jay, a 73 year old female, has been admitted to the hospital for treatment of...

Mrs. Jay, a 73 year old female, has been admitted to the hospital for treatment of a deep vein thrombosis in her right calf. Her PMH includes hypertension. She has been taking Capoten 12.5 mg BID with good control of her pressure.  She is ordered on bedrest with the following orders:

Heparin 5000units IV bolus, followed by a heparin drip of 25,000units in 250ml to infuse at 1000 units per hour. Follow heparin protocol that includes obtaining a stat aPTT 6 hours after initiation and 6 hours after any dose change.

1. How many mL per hour will you administer the heparin drip to deliver 1000 units per hour?

2. What is an aPTT? What is a therapeutic range?

3. How does heparin work? What precautions need to be taken?

4. What is the treatment for a heparin overdose?

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