What is more likely to be associated with a single nucleotide polymorphism (SNP)? common complex traits?...
What is more likely to be associated with a single nucleotide polymorphism (SNP)? common complex traits? or intermediate traits? (based on the frequency and effect size)
Homework Answers
Based on the frequency and effect size across all qualitative disease traits, based on researches it can be concluded that minor alleles conferred “risk” more often than “protection.” Across all traits, an inverse relationship exists between “regression effects” and allele frequencies. Thus single nucleotide polymorphism (SNP) is more likely to be associated with intermediate traits.
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What is more likely to be associated with a single nucleotide
polymorphism (SNP)? common complex traits?...
As it relates to single nucleotide polymorphism, where is the most likely location to find an...
As it relates to single nucleotide polymorphism, where is the most likely location to find an SNP that does not impact protein function? Choose one: O A. within a splice site junction O B. within the middle of an intron O C. within the middle of an exon O D. within the stop codon
In genetics, single nucleotide polymorphisms (SNPs) are locations in the (human) genome that exhibit variation across...
In genetics, single nucleotide polymorphisms (SNPs) are locations in the (human) genome that exhibit variation across the population. SNPs cause the differences we see in traits such as hair color. Each SNP typically has two possible alleles say A and a and each person's genotype at the SNP is either AA, Aa, or aa, where one allele comes from the person's mother and one from the father. Let X be the number of A alleles at a particular SNP, and...
Name: QUESTIONS 38-40: You perform a genome-wide association study (GWAS) to identify genes affecting variation for sun sensitivity and the associated risk of skin cancer, using a sample of 1000 Icel...
Name: QUESTIONS 38-40: You perform a genome-wide association study (GWAS) to identify genes affecting variation for sun sensitivity and the associated risk of skin cancer, using a sample of 1000 Iceland natives with no evidence of mixed ancestry. The genotype-phenotype data for SNP rs 1805007 (a C/T single-nucleotide polymorphism) in the melanocortin-1-receptor (MCIR) gene are shown in the following table. e rar Number of individuals by genotype Phenotype Burning Tanning TOTALS T/T 155 460 615 C/T 110 200 310 C/C...
how are Topological Associated Domains and haplotype blocks related? what could Single nucleotide polymorphisms do to...
how are Topological Associated Domains and haplotype blocks related? what could Single nucleotide polymorphisms do to a Topological Associated Domains?
2.Two different single nucleotide polymorphisms in the ataxia telangiectasia mutated (ATM) gene (rs11212617) are associated with...
2.Two different single nucleotide polymorphisms in the ataxia telangiectasia mutated (ATM) gene (rs11212617) are associated with the response to the glucose-lowering drug metformin which is used in treating type 2 diabetes. These alleles vary in frequency among ethnic populations. In a particular South Indian population, the following genotype frequencies were observed. Calculate the frequencies of the A, C1 and C2 alleles in this population. ' Genotype AA AC1 C1C1 AC2 C2C2 C1C2 Frequency 0.49 0.406 0.0841 0.014 0.0001 0.0058 3....
Explain why case-control studies are considered a more complex observational study? What is a common weakness...
Explain why case-control studies are considered a more complex observational study? What is a common weakness of case-control and observational studies?
Is what I have correct or wrong? The diagrams below show very simplified species relationships for...
Is what I have correct or wrong?
The diagrams below show very simplified species relationships for certain areas of African savanna. Recall what the direction of arrows means for each type of diagram. Then use these simplified diagrams to answer the next 3 questions. (Note: Real-world savannas support more species with more complex relationships.) Savanna Food Web Lions Cheetahs Elephants Zebra Gazelle Trees Shrubs Grasses Competition Among Savanna Plants Trees Shrubs Grasses Q5.6. If you removed all the Lions from...
Human Genetics Although we humans are fantastically made, are quite complex, and our traits are often...
Human Genetics Although we humans are fantastically made, are quite complex, and our traits are often coded by many genes, some traits are coded by single gene pairs. The following table is a survey to help you determine your genotype, based on phenotype traits. Keep in mind the terms homozygous dominant (AA) will have the dominant trait, homozygous recessive (aa) will have the recessive trait, and heterozygous (Aa) will have the dominant trait. If you have the dominant trait, you...
A common size analysis requires the representation of financial statement data in terms of a single...
A common size analysis requires the representation of financial statement data in terms of a single financial statement item (or base account or value). What is the most commonly used base item for a common size income statement? O Net sales Total assets Stockholders' equity O Total liabilities Suppose you are conducting an analysis of the financial performance of Cute Camel Woodcraft Company over the past three years. The company did not issue new shares during these three years, and...
What are the three functional groups that comprise a nucleotide? What do nucleotides have in common...
What are the three functional groups that comprise a nucleotide? What do nucleotides have in common with amino acids or simple sugars? When the structure of DNA was first elucidated, many biologists quickly saw how this structure explained the passage of information from one generation to another. How does the structure of DNA explain generation-to-generation flow of information? In other words, give a brief description of the structure of DNA and tell how this structure allows for replication. Which of...
As it relates to single nucleotide polymorphism, where is the most likely location to find an SNP that does not impact protein function? Choose one: O A. within a splice site junction O B. within the middle of an intron O C. within the middle of an exon O D. within the stop codon
In genetics, single nucleotide polymorphisms (SNPs) are locations in the (human) genome that exhibit variation across the population. SNPs cause the differences we see in traits such as hair color. Each SNP typically has two possible alleles say A and a and each person's genotype at the SNP is either AA, Aa, or aa, where one allele comes from the person's mother and one from the father. Let X be the number of A alleles at a particular SNP, and...
Name: QUESTIONS 38-40: You perform a genome-wide association study (GWAS) to identify genes affecting variation for sun sensitivity and the associated risk of skin cancer, using a sample of 1000 Iceland natives with no evidence of mixed ancestry. The genotype-phenotype data for SNP rs 1805007 (a C/T single-nucleotide polymorphism) in the melanocortin-1-receptor (MCIR) gene are shown in the following table. e rar Number of individuals by genotype Phenotype Burning Tanning TOTALS T/T 155 460 615 C/T 110 200 310 C/C...
Is what I have correct or wrong?
The diagrams below show very simplified species relationships for certain areas of African savanna. Recall what the direction of arrows means for each type of diagram. Then use these simplified diagrams to answer the next 3 questions. (Note: Real-world savannas support more species with more complex relationships.) Savanna Food Web Lions Cheetahs Elephants Zebra Gazelle Trees Shrubs Grasses Competition Among Savanna Plants Trees Shrubs Grasses Q5.6. If you removed all the Lions from...
A common size analysis requires the representation of financial statement data in terms of a single financial statement item (or base account or value). What is the most commonly used base item for a common size income statement? O Net sales Total assets Stockholders' equity O Total liabilities Suppose you are conducting an analysis of the financial performance of Cute Camel Woodcraft Company over the past three years. The company did not issue new shares during these three years, and...
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