Question

Explain why case-control studies are considered a more complex observational study? What is a common weakness of case-control and observational studies?

Answer 1

A case–control study is a type of observational study in which two existing groups differing in outcome are identified and compared on the basis of some supposed causal attribute.

This study involves studying two different groups who exposed to same risk factors but they are vary in outcome.

Case control study is more complex observational study because,

• it is difficult to maintain the study group and control group.
• During sample selection there is chances of bias.
• Case control study require fewer resources but provide less evidence for causal inference than a randomized controlled trial.

Common Weakness of case control and observational studies:-

• Subject to many bias
• Limited control over the composition of control group