Question

Regular insulin is used to treat Diabetic Ketoacidosis. Explain the rationale of using regular insulin rather than NPH insulin.

Answer 1

Ans)

As we know that regular insulin delivery is very important in the Diabetic ketoacidosis,the reason for this is that it encourage the glucose usage by the peripheral tissues, decreases gluconeogenesis and glycogenolysis and repress ketogenesis.Administration into vein is the better way of providing insulin in the individuals with diabetic ketoacidosis.

NPH insulin- Intermediate-acting insulin

Regular insulin- Short acting insulin

The NPH insulin is usually used to manage blood glucose range in the individuals with diabetes.This is administered via injection beneath the skin( Subcutaneously).

Usually short-acting insulin is preferred for the righting of the hyperglycemia.The subcutaneous assimilation of insulin is lower in diabetic ketoacidosis due to dehydration,;so, utilization of intravenous path is better.

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