Question

5. propose an efficient synthesis plan for each of the following reactions.

6.Before moving on to N-nucleophiles, let’s check your memory on some ketone reactions.

5. Now, straight from our textbook, propose an efficient synthesis plan for each of the following reactions. ره ماه را OH و . Ph Ah 6. Before moving on to N-nucleophiles, let's check your memory on some ketone reactions. 1. PhMgBr 2. H30* NaBH4, EtOH 1. LAH 2. H2O Zn(Hg), HCI

Answer 1

HD do 7 H NONH₂ protect ketone carth diel Acetelide formahan as I d ] W 13ota > products a E Deprotection of Adebay t SN Reacton can C-al keglatan & i Hor dt, HO DLAlty protect castoral with 12 diel 8 Hota V olt Acetal de protections LalHa reduce - Ester Hodt, Ho 6 d. to u primary alcohol pochecton & ketene llophing Brc Encess) olt ph Hzet, a 'ph Deprotactan "ph

1 phanger 2) H3- CH2 NOB Hy stelt 아 HO LCH? NaBty reduce ketone to 20 alcohol grignard for produce su alcohol from ketone Clemensan Reductan Zn Hs) Ha i Latt OH ketone redund to CH LAH Wtho reduce ketone to 20 alcona En C-0 CH demension reduction