4. The transformation of the alkyl chloride shown below into the alcohol can be accomplished in...
4. The transformation of the alkyl chloride shown below into the alcohol can be accomplished in two steps. Show the synthetic scheme to finish the conversion. (I point) ОН
3. Give the structures of the two products for addition reaction of HCI to 3-methyl-1-pentene (1 point), Point out which one is the major product, and explain why! (Hint: dont forget carbocation rearrangement) 4. The transformation of the alkyl chloride shown below into the alcohol can be accomplished in two steps. Show the synthetic scheme to finish the conversion. (1 point) OH
Bonus 3. Give the structures of the two products for addition reaction of HCl to 3-methyl-1-pentene (1 point). Point out which one is the major product, and explain why! (Hint: dont forget carbocation rearrangement) 4. The transformation of the alkyl chloride shown below into the alcohol can be accomplished in two steps. Show the synthetic scheme to finish the conversion. (1 point) Он Br
1. Give the structure of the product(s) for the following addition reactions. Show appropriate stereochemistry if necessary to get the full credits. (5 points) 50% H2SO4 50% H20 1. BH3, THF 2. H2O2/KOH CH3COOH ry condon YY PEO 1. 03 2. Zn/H2O 2. Give the syn or anti addition products for the following addition reactions. Show appropriate stereochemistry if necessary to get the full credits. (5 points total) Hz/Pt 1 point 1 point Hypt DBk Det ook o BryH2O 1....
For each of the transformations below, provide the reagents necessary. Each transformation can be accomplished in 4 or fewer steps. Be sure to indicate stereochemistry where relevant!
Question 10.16 The following alkyl chloride can be prepared by reaction of the alcohol QR)-2-pentanol with SOcly alkyl chloride, including (R) or (S) stereochemistry, and tell whether the reaction of the alcohol occurs with retention of the same stereochemistry or with a change in stereochemistry ball & stick (t is not necessary to use italics in writing compound names. The answer field is case-sensit Name: Stereochemustry:ーーーーリ Try Another Versio 7 iteen astempts remaining Submit Answer
The following transformation can be easily accomplished under either of the conditions shown. Provide a complete arrow-pushing mechanism for each of these methods to accomplish the transformation (10 points total, 5 points each mechanism). NaOH ОН ОН
13 SN1: Synthesis of tert-Butyl Chloride Alkyl halides can be prepared from their corresponding alcohols via an acid catalyzed substitution reaction. The mechanism of these acid catalyzed substitution reactions are labeled as Syl (substitution, nucleophilic, unimolecular) and S2 (substitution, nucleophilic, bimolecular). Tertiary alcohols follow the Snl route, primary alcohols follow the S2 route, and secondary alcohols can follow either path. Under acidic conditions, the mechanism (Figure 1) of the Sul reaction involves rapid protonation of the alcohol, followed by the...
13 SN1: Synthesis of tert-Butyl Chloride Alkyl halides can be prepared from their corresponding alcohols via an acid catalyzed substitution reaction. The mechanism of these acid catalyzed substitution reactions are labeled as Syl (substitution, nucleophilic, unimolecular) and S2 (substitution, nucleophilic, bimolecular). Tertiary alcohols follow the Snl route, primary alcohols follow the S2 route, and secondary alcohols can follow either path. Under acidic conditions, the mechanism (Figure 1) of the Sul reaction involves rapid protonation of the alcohol, followed by the...
Problem 4 In the synthesis of prazosin shown below, show mechanisms for the first two steps (you only need to show one alcohol group being converted to the chloride in step 2). OH CH30C OOH CH30 SOCl2 CH30 yy NH3 + NaOCN ANOH CH30 CI CH30 CH30 NH2 NH2 NH2 H-N CH30 CH30 CH2O CH30