Problem 4 In the synthesis of prazosin shown below, show mechanisms for the first two steps (you only need to show one...
Problem 2 In the synthesis of the antipsychotic drug, haloperidol, shown below, show mechanisms for the first two steps. (Hint: the second step is likely to proceed by through opening of the 1,3-oxazine ring, followed by dehydration, and a new cyclization.) Cl CH3 - CH3 N HCI / CH20 CRC=CH2 – LOH 1. HBO 2. NaOH HCI I- OH - Planner . ??? C-CH2-CH2-CH2-N H
4. Propose a synthesis to create 3,4-dimethyl-3-hexanol from 1-butene. You only need to show individual steps and reagents, you do not need to show mechanisms. You must use 1-butene as your ONLY source of carbon atoms. The convergent processes have been outlined for you. for STEP 1: Show how to synthesize butyl magnesium bromide from 1-butene (5 points): BrMg STEP 2: Show how to synthesize 2-butanone from 1-butene (5 points): STEP 3: What intermediate forms below and what reagent(s) will...
Problem 5 Show mechanisms for the three steps of the synthesis of oxymetazoline, shown below: но сHз HO CH3 HO CH3 CH20/ HCI NaCN H2NCH2CH2NH2 (CH3)3C (CH3)3C CH2C1 (CH3)3CT CH2CN — сHз CH3 mone, ma non veram, CH3 Z- (CH3)3C CH3
1) Choose one molecule from the set and create an 8-step synthesis scheme using the chosen molecule as your starting material. You need to write the complete set of reagents and draw the product expected from each step. Reagents typically used together are considered one step, eg. 1) LAH 2) H.O should be considered as one step Your 8 steps must include at least one reaction from each of the chapters, aldehydes and ketones, carboxylic acid derivatives, alcohols. You can...
the steps are B,D,H,I,G,D,F,D,C
Synthesis You need synthesize cyclopentanone starting with the lactone shown below in 9 steps where 3 of the steps are acid workups. Cheat DH,O (aqueous acid) E pcc F NaOH, heat G NaOCHCH H Na,Cr,0,.aq acid HOCH,CH,, acid, heat NBS Note- there are 3 reagents on this table that are not used - ALL OTHERS ARE USEI Steps Reaction names Give the name of the type of reaction for each step, (examples: acidification, reduction, saponification decarboxylation,...
can you please show the work.. thank you
in Black New Tab MyUn Sign in Learn @ cheggc GetH Mic x Sign .pdf 1) Choose one molecule from the set and create an 8-step synthesis scheme using the chosen molecule as your starting material. You need to write the complete set of reagents and draw the product expected from each step. Reagents typically used together are considered one step, e.g. 1) LAH 2) H20 should be considered as one step....
how do you solve for these?
HOW
DO YOU SOLVE THESE QUESTIONS STEP BY STEP MECHANISMS
3. Show a mechanism for the following (Grant Challenge). Hint at end with * if you need it. - this is for the people that want a big challenge and who are already very comfortable with mechanisms. 3. Na2CO3, H, 0 0 4. Propose a synthesis for the following, starting from methanolas your only carbon-based starting material. ool logo Me 5. Classify the following...
Experiment 12: Synthesis of Benzoic Acid pre-lab (4 pts) 1 (2 pts) Refer to the introduction on the general process of hydrolysis of nitriles to carboxylic acids. Starting with benzonitrile (shown below), show how it is converted to benzoic acid under basic conditions. N 2) (2 pts) The reaction for the synthesis of benzoic acid via benzonitrile hydrolysis is shown below: 1) NaOH, HO YOH + NaCl 2) HCI, H,0 Benzonitrile Density = 1.0 g/mL MM = 103.04 g/mol Benzoic...
need help with the boxed bullet point. writing the chemical
reaction scheme for the experiment.
Synthesis of an Alkyl Halide: A Nucleophilic Substitution Reaction, Part I Pre-lab Assignment for Synthesis of an Alkyl Halide: A Nucleophilic Substitution Reaction, Part 1 1. From The Organic Chem Lab Survival Manual ( edition) by Zubrick • Review pages 201-204: Standard Reflux. • Review pages 127-140: Extraction • Review pages 164-189: Distillation, Simple Distillation. The Distillation Example, and The Distillation Mistake. 2. Read this...
HC-C+ CH2 CHs a) Icll 11 c) III</</I d) l 11K1 Part B ) Please show how to do the synthetic transformations shown below (You may need multistep synthesis, that is several steps may be needed ). (5 points each). You may only use reactions and molecules described in chapters 1-12 of the textbook. A) он CHM 250 Spring 2019 Final Exam CHM 250 B) C) O N 12
HC-C+ CH2 CHs a) Icll 11 c) III