Problem 5 Show mechanisms for the three steps of the synthesis of oxymetazoline, shown below: но...
Problem 2 In the synthesis of the antipsychotic drug, haloperidol, shown below, show mechanisms for the first two steps. (Hint: the second step is likely to proceed by through opening of the 1,3-oxazine ring, followed by dehydration, and a new cyclization.) Cl CH3 - CH3 N HCI / CH20 CRC=CH2 – LOH 1. HBO 2. NaOH HCI I- OH - Planner . ??? C-CH2-CH2-CH2-N H
Problem 4 In the synthesis of prazosin shown below, show mechanisms for the first two steps (you only need to show one alcohol group being converted to the chloride in step 2). OH CH30C OOH CH30 SOCl2 CH30 yy NH3 + NaOCN ANOH CH30 CI CH30 CH30 NH2 NH2 NH2 H-N CH30 CH30 CH2O CH30
show the steps in the synthesis reaction (reactant and final
products shown)
Synthasis prablans + Но Br бн. Br t En + En
Please go through each step of this synthesis problem and show
each reactant bwtween steps! It is very important that they are
correct so please make sure your answer is right! thank you so
much!
E. SYNTHESIS: (12 points) cohols, alkenes synthesize the molecule below using any of the following reagents: a and/or alkynes of three carbons or less, any inorganic reageAts, any oxidizing or reducing agents, and any peroxyacids. DO NOT GIVE MECHANISMS. HO OH HO
3. SURResta synthesis for each of the compounds shown below, beginning with the compound shown on the left. Clearly show all required reagents and intermediates Mehr HO но NO NHL-NH.KOH NH, NHL-NHKOH I reali HO CH.CH COH SOA NH Сн,CH, 2 CHOH Nathanol Η O' 1,0 4. Suggest a synthesis for each of the compounds shown below, beginning with the starting material shown on the left. Clearly show all intermediates and reaction conditions. Multiple steps are likely to be required....
i (6 pts) Show detailed arrow includin tautomerization steps for the formation of a neolignan a alcohol shown below. ing mechanisms, including all resonance structures and nd a lig OH OH он он HO Ho 7. (10 pts) Draw out the biosynthetic process for the formation of myristicin from phosphoenylpyruvate (PEP) and erythrose-4-phosphate. Make sure to write out important intermediates involved он Ho H3co но' o он о 0 myristicin
i (6 pts) Show detailed arrow includin tautomerization steps for...
Please explain the mechanisms!
1. Propose a synthesis for each of the following problems starting with reagent shown and using any other organic or inorganic reagents allowed in each problem. Multiple steps are required. The number of steps you use does not matter. Reactions should give the desired product as a major product. For full credit show the product of each step (reaction). If you make use of organometallic reagents such as Grignard, Wittig, organolithium, organosodium, organocopper, etc. you must...
5. Provide a synthetic route for each transformation shown below. For full credit, show the product formed after each step of the synthesis. HO Br O SCHy
5. Provide a synthetic route for each transformation shown below. For full credit, show the product formed after each step of the synthesis. HO Br O SCHy
Please help woth mechanisms and answers for these!
5. Shown below is the mechanism presented for the formation of biasplatin in reference 1 from the Experiment document. The amounts used of each reactant are shown. Either draw or describe a better alternative to this mechanism. (Note that the first step represents two steps combined and the proton loss is not even shown; fixing these is not the desired improvement.) 0.15 mmol 1.1 mmol 4. The acetylation of salicylic acid may...
1. Predict the major product for the reactions shown below; pick any 5: HO xs CHal Ag20 NaOEt EtOH, Δ -H2O HO но он 0 он H2SO4 H20, A heat 1) PhMgBr 1) NaOH, Br2 2) 5% HCI 2)H3O+, Δ OEt 1) PPh3 3) KOtBu 2) O 1) NaOH on. Br 2) O o
1. Predict the major product for the reactions shown below; pick any 5: HO xs CHal Ag20 NaOEt EtOH, Δ -H2O HO но он 0 он...