Question

4. The following reaction is a Robinson annulation reaction: a cascade reaction! of a loca no NaOET aglo .no OEt + H20 heat In true research style, we need to figure out how this reaction happens. Let's investigate! a. Circle each reactant in the product and determine the new bonds formed. b. Identify the functions of both reactants - reflect on what we discussed on days 14-15! What would be the first reaction? of info — c. List the structural features of the isolated product. What reactions coincide with these features?

Answer 1

Please refer below image it will help you

Here in 2 the first reaction is keto enol and then attack of enol on alpha beta unsaturated ketone and then again ring formation takes place as shown below;

(Rare 22 06+ NAOH Heat O6 + H2O - -- B new bond newbond 10 fost reaction would be Koto onol fantomensmas. IOGA ce Oct CH3 06 och CH3 o uomo 03 rona 9 Mo © structural features Ester group 6 memb ring + , B unsaturated ketone