2. Draw the structures of the analgesics ( acetaminophen, aspirin caffeine and ibuprofen) employed in this experiment. Arrange them in order of increasing polarity.
2. Draw the structures of the analgesics ( acetaminophen, aspirin caffeine and ibuprofen) employed in this...
2. Aspirin, acetaminophen, and caffeine are some of the substances being tested in this TLC experiment. Look at their structures and atoms present to help you explain why 100% hexane would NOT be a good TLC developing solvent (chromatography solvent) to use in this Thin Layer Chromatography experiment.
Draw the structures of acetaminophen and ibuprofen . Do these compounds have similarities? Differences? What are they?
Extra-strength Excedrin is a combination of 250 mg acetaminophen 250 mg aspirin, and 65 mg caffeine plus inactive ingredients that are insoluble in water and organic solvents. Using the data in Table E9.1. draw a flowchart to show how these three components could be sepa- rated using their solubility and acid-base properties. Hint: Caffeine is a nitrogen base similar in reactivity to diisobutylamine (Section 7.6.1 and Experiments 2 and 7). HN OH NN OH acetaminophen aspirin caffeine
1. Propose a synthesis for aspirin, Ibuprofen and acetaminophen. Start with benzene and any other reagents that contain 4 or less carbons. 2. What error is introduced into the determination of an Rf value if the solvent front migrates to the top of the TLC plate? 3. Why is the TLC run in a closed chamber?
Analgesics and Bowel Medications 1. Is acetaminophen an NSAID? Why or why not? Opioid Analgesics 2. Why would the physician order acetaminophen rather than a salicylate? 1. When would a nurse anticipate orders for opioid analgesics other than fentanyl? 3. What is the maximum dose of acetaminophen? 2. What other use do opioid have? 4. What is the antidote for acetaminophen toxicity? 5. What interactions should the nurse be concerned with? Antidiarrheals: 3. The most serious adverse effect of opiods...
You are asked to analyze the following two solutions: Solution 1 – acetaminophen, ibuprofen, and aspirin Solution 2 – methyl t-butyl ether, isooctane and n-butanol (gasoline additives) Explain which chromatographic technique (GC or HPLC) you would use to separate each of these mixtures and why that technique would be useful for that separation. Indicate columns and detectors when appropriate.
2. Draw structural formulas of the following compounds. Circle and idet are present in each compound. llowing compounds. Circle and identify the functional groups that a. Aspirin b. Ibuprofen c. Acetaminophen d. Caffeine 11-1
2. While caffeine is very soluble in water, aspirin is only minimally soluble. a. Clearly explain why you think caffeine is soluble in water. b. In order to dissolve the aspirin, I had to use a sodium hydroxide solution (this is why you had to add HCl to the separatory funnel.) Clearly explain how the use of a sodium hydroxide solution allowed the aspirin to dissolve. Structures/reaction(s) will likely help your answer.
2 Draw the structures of the other alcohols which are isomeric with tert-butanol. Arrange these alcohols in order of INCREASING reactivity toward concentrated HCI to give the corresponding alkyl chloride under such conditions.
Draw molecular structures of bromobenzene, benzophenone, and triphenylmethanol and biphenyl in the order of increasing polarity (east polar < most polar).