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QUESTION 9 Preformed mediators that are released during the activation phase of a Type I Hypersensitivity response include wh
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Q.9. Histamine is immediately released from the preformed granules during the activation phase of Type I hypersensitivity response, hence it is called as a preformed mediator, while the other mediators like cytokines, chemokines, and leukotrienes are released and activated later on in a cascade of reactions. Thus option C is a correct response.

Q.10. Cytotoxic T cells normally express the CD8 in the thymus by the involvement of CD8 α & CD8 β chains while some negative natural killer cells also express the CD8. Means both express CD8. Hence option D is correct.

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