Question

Case Study 2 Antihistamines An eight-year-old child is brought into the clinic by her mother Each year in the spring, the chil eyes and sneezing. She was treated in the past with diphenhydramine. But her teacher said it made her drowsy during school. She has no other medical problems and is not on any chronic medications. Her unremarkable. The physician diagnoses her with seasonal allergic rhinitis and prescribes fexofenadine d develops a runny nose, watery phy sical examination is . What is the mechanism of action of the antihistamines? (25 points) 2. What is the most common side effect of the antihistamines? Name 4 other adverse effects of antihistamines. (25 points) . What is the pharmacologic basis of switching to fexofenadine?( 25 points) What instructions would the nurse give to the child's mother about administering the fexofenadine? (25 points)

Answer 1

tHistomine it prent in all the Hrves, oith signif cot amounts in the lungs, skin, blood vossels, and Hisbmine ic lormed by the decarboxy lation o hishdine by hichdine decarbonylase The chinul or release hic tomine from heres may indue oles truc tion ok cells Those dnugs which anta gopize bad Jeck by blocking or hhibitrt histamine ahe calledonhhis tamine Yecepors Antihistamines [ethanism of hchon] Fiest genesation dugs - fenetrate the CNS cause seond generahon Do not pehehrate the Se da tion BBB causing leas -interact hoith other recestoxs producing adverse eftect x Compion Side efets the fiast gendrahon Advese ekkect S leepinas Headache Behavioral change Rashes mouth Con juion Fexalenadlinegtbthe eond gwh o an ti his tamines which causes less cNS e lo dut ression んhich also decreases drooz new Dnug should nat be tonsumed horth fuid fjuze as gate 〕ula mad decrease the Senemt ton entations{ Fexofena dine