You perform an ABO typing and note that a RBC suspension agglutinates with Anti-A and not...
You perform an ABO typing and note that a RBC
suspension agglutinates with Anti-A and not with Anti B. What
antigen is on the surface of that red cell? A second
specimen does not agglutinate with either Anti-A or Anti-B.
What antigen is on the red cell surface?
Homework Answers
There are two antigens present on the RBC.Antigen A and antigen B are present on the surface of RBC.They are called agglutinogens.They cross react with antibodies Anti A and Anti B antibodies.When RBC suspension agglutinate with Anti A and not with Anti B then the Antigen A is present on the RBC and when it does not agglutination is with either of anti A or Anti B then no antigens are present on the RBC surface.
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You perform an ABO typing and note that a RBC
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Background INFO
There are four types of blood: A, B, AB, and O (Figure 4). Each
is characterized by the glycoproteins (proteins with a sugar
attached) and lipoproteins (proteins with a lipid attached)
embedded in the surface of red blood cells (RBCs). In addition to
type, blood can be rhesus (Rh) factor positive or negative.
These proteins are inherited and may differ from individual to
individual. If, during a transfusion, an individual receives
blood with the incorrect RBC proteins (for...
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system in class, you can find a brief explanation below and
here.The I gene encodes for a glycosyltransferase
that modifies at the H antigen.The glycosyltransferase encoded by IA adds an 'A'
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glycosyltransferase that leaves the H...
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History:
V is a 52-year old woman who just underwent surgery that
resulted in the need to transfuse two units of red blood cells. V
has three children and has reported to have been transfused twice
in the past.
6. Which of the
following antibodies remain after completion of the antibody
identification (completion of panel antigram)? (2 pts)
A.
Anti-Jsa
B.
Anti-Lub
C. Anti-e
D.
Anti-Jkb
7. Given the
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hypothesis...
Human blood types A, B and O are associated with the carbohydrate antigens A, B and H respectively. A and B antigens are caused by an alteration of H antigen. Normally everyone can synthesize H antigen (a cell surface carbohydrate found on red blood cells and other cell types). Some people make A and/or B transferase(s) which converts the H antigen to an A and/or B antigen respectively. The H antigen is produced by a specific fucosyltransferase encoded by the...
nyia Ayla) Exercise 4.5 Following antibody identification, your patient possesses anti-K, anti-Jk", and anti-E. How many RBC units do you need to screen to find two antigen-negative RBC units? The antigens occur in the population with the following frequencies: E+ = 30%; K+ = 9%; Jk(a+) - 77%. Exercise 4.6 You performed a population study on your class and found that 84% are D-positive. Using the Hardy-Weinberg calculation, determine the percentage of your classmates who are heterozygous for D antigen....
Background INFO
There are four types of blood: A, B, AB, and O (Figure 4). Each
is characterized by the glycoproteins (proteins with a sugar
attached) and lipoproteins (proteins with a lipid attached)
embedded in the surface of red blood cells (RBCs). In addition to
type, blood can be rhesus (Rh) factor positive or negative.
These proteins are inherited and may differ from individual to
individual. If, during a transfusion, an individual receives
blood with the incorrect RBC proteins (for...
Blood Typing Here is the activity we were going to do in lab. Please read and fill in the data table: Obtain a slide and place a drop of anti-A, anti-B, and anti-Rh (in three SEPARATE spots) on the slide. Choose a synthetic blood sample and mix a drop of blood with each of the antisera (A, B, and Rh). Mix the blood and antiserum together using a clean toothpick. Don't reuse toothpicks or mix samples. The antiserum contains the...
Forward Typin Anti-B Reverse T Ai cells Auti-A Anti B cells M a 48-year-old woman, presented to the physician with a long history of dysfunctional uterine bleeding. She complained of chronic fatigue, hcadache, and a general malaisc. Upon admission to your institution her hemoglobin level was 7.5 mg dL. She was scheduled for an abdominal hysterectomy the following day and the surgcon requested three units of red cells to be given prior to the surgical procedure. Mbad no history of...
The ABO blood groups.There are three main alleles in the ABO blood group system -
IA, IB, and i. We've talked about the ABO
system in class, you can find a brief explanation below and
here.The I gene encodes for a glycosyltransferase
that modifies at the H antigen.The glycosyltransferase encoded by IA adds an 'A'
sugar group to antigen H, the glycosyltransferase encoded by
IB adds a 'B' sugar group and i encodes an inactive
glycosyltransferase that leaves the H...
Forensics Blood Typing Imagine you are a CSI detective. You have just arrived at a house that someone had broken in through a glass door. The intruder cut himself with the broken glass and some blood was left behind on the crime scene. You have collected blood samples from the crime scene. The police have called you because they have 3 suspects in custody. The chief investigator has asked you to help him to narrow down suspects using blood typing....
History:
V is a 52-year old woman who just underwent surgery that
resulted in the need to transfuse two units of red blood cells. V
has three children and has reported to have been transfused twice
in the past.
6. Which of the
following antibodies remain after completion of the antibody
identification (completion of panel antigram)? (2 pts)
A.
Anti-Jsa
B.
Anti-Lub
C. Anti-e
D.
Anti-Jkb
7. Given the
patient history and all serology results, what is the best
hypothesis...
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