3. Give the major organic aldol product for each reaction, along with the dehydration product (if...
4. In the following reaction the aldol product C is difficult to isolate, and even without heating the dehydration product D is formed instead. Explain. ОН н NaOH Н Н.о н С 5. Draw all possible aldol products from this mixed aldol reaction (not dehydrated). NaOH + Н.о H 6. Give the major organic product from each mixed aldol reaction. Then explain why the reaction conditions favor one product instead of generating a mixture of products. NaOH a. Но Н...
6. Give the major organic product from each mixed aldol reaction. Then explain why there conditions favor one product instead of generating a mixture of products. NaOH HO H CCI, NaOH HO a. LDA ht 7. Give the curved arrow mechanism for this reaction. he NaOH, H2O heat halla Τ Η 3. Give the major organic aldol product for each reaction, along with the dehydration product possible) formed after heating. NaOH heat H2O heat NaOH H2O ix heat NaOH HO
6. Give the major organic product from each mixed aldol reaction. Then explain why the reaction conditions favor one product instead of generating a mixture of products. NaOH a. + Н,о "СС, NaOH b. Н.о a. LDA c. b. О H н 7. Give the curved arrow mechanism for this reaction. NaOH, H,O Н heat
9. Give the major organic product of each intramolecular Aldol reaction. NaOH, H2O heat NaOH, H2O b. H heat NaOH,H,O NaOH, H2O heat 168
Draw the structure of the major aldol product (prior to possible dehydration) of the following reaction 10% aqueous NaOH 25° You do not have to consider stereochemistry. If no reaction occurs, draw the organic starting material.
8. Give the major organic product of each reaction. NaOH,H,O c. mild H a. LDA b. مل، بل NaOH,H,O, heat c. mild H NaOH, H2O NaOH,H,O ) 9. Give the major organic product of each intramolecular Aldol reaction. NaOH,HO heat NaOH, H20 heat NaOH, H0
Condensation Reactions Homework (Chapter 19) NAME 1. Explain why aldehyde A is more reactive to nucleophilic addition reactions than ketone B. 2. Give the curved arrow mechanism for each aldol reaction. est NaOH, H, heat NaOH, H, heat 3. Give the major organic aldol product for each reaction, along with the dehydration produs possible) formed after heating. NaOH H,0 heat NaOH heat HO heat NaOH HO
Draw the structure of the major aldol product (prior to possible dehydration) of the following reaction ol dilute NaOH 95% aq ethanol, 0-5° . You do not have to consider stereochemistry If no reaction occurs, draw the organic starting material . P С Oy Z [
Draw the structure of the major aldol product (prior to possible dehydration) of the following reaction (References] CHE + CH 5% NaOH 95% aq, ethanol. 30° Сн, н • You do not have to consider stereochemistry. If no reaction occurs, draw the organic starting material P opy C- 7 (
7. Predict the major organic product or provide reagents needed to complete each reaction. 1. CH3NH2 (a-b) excess 2. LIAIHA 3. H20 ia -NH ?? excess (c-d) HO NH2 triethylamine ? (e-f) CEN 1. CHẠMgBr 2. H20, H NH2 (g-h) H20, H* H2. Pd (1-1) CH3NH2 4 products (m) 1. LAIH 2. H2O, H & NH (n) 1. LiAIH4 2. H20, H+ 8. Predict the four possible Aldol condensation products and their dehydration products. KOH, H20.A + H 1. Predict...