Question

Epidemiology homework help!

Question 1

What was the major concern that was missing in the multicenter Hypertension Detection and Follow-up Program (HDFP) study?

		lack of blinding
		lack of randomization
		lack of an untreated placebo group
		publication bias
		ethical concerns

Question 2

An experiment in which neither the experimental unit not the researchers in contact with the experimental unit knows which treatment the experimental unit is receiving is called a ____.

		Randomized experiment
		Single-blind experiment
		Double-blind experiment
		Matched pair design
		Cohort study

Question 3

What phase of a drug trial would definitely include randomization?

		Phase I
		Phase II
		Phase III
		Phase IV
		Phase V

Question 4

Suppose the mortality rate is an untreated group is 33% and mortality in the treated group is 26%. Estimate the number of patients that would need to be treated (NNT) to prevent an adverse outcome such as death.

Question 5

A medical researcher is working on a new treatment for a certain type of cancer. The average survival time after diagnosis on the standard treatment is two years. In an early trial, she tries the new treatment on three subjects who have an average survival time after diagnosis of four years. Although the survival time has doubled, the results are not statistically significant, even at the 0.10 significance level. Suppose, in fact that the new treatment does increase the mean survival time in the population of all patients with this particular type of cancer. Which of the following statements is true?

Type I error has been committed.

Type II error has been committed.

No error has been committed.

Question 10

What is the main advantage of a cross-over or matched pair design?

Individual is their own control, removing any various for individuals

It avoids carry over

It is unplanned

It takes less time

The individual is not required to be compensated