Question

i need help with questions 1 and 2

1. [6 pts] Identify the following statements as applying to acute or chronic exposures. Often requires a lower exposure to achicve the same endpoint. a. An exposure that occurs for two months b. An exposure that requires a high dose to cause an impact over a short C. duration. 2. [8 pts] Identify which metric of toxicity would be best suited to measuring the following endpoints. An endpoint may be used more than once (or not at all). ED LD LC Metric of Toxicity Endpoint Inhibition of an enzyme Increase in number of tumors Mortality from an intravenous injection Mortality to fish in an aquatic exposure

Answer 1

DU 1 La) Acute (b) Chronic (C) Acute Imbiaon of enzyme: EDS0 hibl Effective dose) usually TCse i wed 2. 50 Imcrease in umber of tunmors: IDso (Infective dose) Lemal dese) Mortality from an inbravenous mjectien: LD50 ho Mortaliby pema in an aavalic exposuve: LCso Lethal conenbatan)