Question

CASE STUDY: OSTEOPOROSIS MEDICAL HISTORY Mrs. Bone, a 62 yr old Caucasian woman, is referred by her physician for the development of an exercise prescription. She is 10 yr postmenopausal and has never been on hormone replacement therapy. She was diagnosed with hyperthyroidism Coveractive thyroid gland), which was treated with radioactive iodine. Since the treatment, Mrs. Bone has been on synthroid, a drug used when the thyroid gland does not produce enough thyroid hormones. She has mild hypertension, which is regulated by her blood pressure-altering medications. Mrs. Bone is 5 ft 5 in (165 cm) tall with a weight of 128 lb (58 kg), and her BMI is in the normal range. She does not currently exercise. BONE DENSITOMETRY Test The bone densitometry test (DEXA) revealed osteopenia. DISCUSSION QUESTIONS Define bone mineral content, bone mineral density, and trabecular bone. What is her diagnosis? What other information should be obtained from this patient? What other physiological tests might be recommended?

Answer 1

1. BOne mineral content is defined as ratio between mineral weight and bone sample dry weight

bone mineral density defines bone strength by finding bone calcium content

trabecular bone is bone which is porous and made up of trabeculated bone tissue. It is found at the ends of long bones.

2. osteoporosis is bone condition in which bones become porous and brittle as bone formation is less as compared to bone loss.
3. other information include smoking history, certain medications like heparin, phenytoin, corticosteroids, other commorbidities like arthritis, hepatitis c , liver infection, diet pattern

4. Other tests include blood calcium level, 24 hr urine calcium, thyroid function test, parathyroid function test, biochemical marker tests like CTX and NTX