Question

Which of the following are characteristics of opioid agonists - antagonists? Select all that apply Produce a weaker pain response than full opioid agonists. Have a greater abuse potential than pure opioid agonists Produce less respiratory depression than full opioid agonists. Act as antagonists on mu receptors and agonists on kappa receptors

Answer 1

Option C and D are correct because Mixed oioid agonist-antagonists like pentazocine produce agonistic action on kappa receptor and antagonistic action on mu receptors, having more analgesic action /pain response than full opiod agonists, have lower abuse potential than pore opiod agonists and have lesser respiratory depression than pure oioidal agonists