Question

​​​​​​Please answer the following, Thanks

11. Give two contraindications for the medication "Levothyroxine"

      12. Give two medication interactions for Synthyroid and provide a rationale.

      13. Give two food interactions and provide a rationale.

14. Give two nursing administration consideration for Synthyroid.

Adrenal.

15. Fill in the following table. Give a brief description of disorder in your own words. For each side effect describe the intervention and education. (The disorder is given, please fill in the rest).

Disorder and Medication	Side effects (Give 3)	Nursing Intervention/Client Education
Addison’s
Cushing’s

16. Name one condition that is contraindicated for medications used to treat Addison’s disease.

17. Name one condition that is contraindicated for medications used to treat Cushing’s disease.

18. Fill in the following table. Give a brief description of disorder in your own words. For each side effect describe the intervention and education. (The disorder is given, please fill in the rest).

Disorder and Medication	Side effects (Give 3)	Nursing Intervention/Client Education
Conn’s syndrome
Pheochromocytoma

Answer 1

Contraindications for levithyroxine:

• overactive thyroid gland
• thyrotoxicosis crisis
• diabetes
• pituitary hormone deficiency
• a condition where the adrenal glands produce less hormones called Addison's disease
• osteoporosis
• a condition of weak bones
• decreased calcification or density of bone

13:Aluminum and magnesium containing antacids, calcium carbonate, simethicone, or sucralfate and iron-containing compounds may decrease the absorption of Synthroid;

14:absorption of levothyroxine may be decreased by foods such as soybean flour, cotton seed meal, walnuts, dietary fiber, calcium, and calcium fortified juices. These foods should be avoided within several hours of dosing if possible.

15:Addison's disease, also called adrenal insufficiency, is an uncommon disorder that occurs when body doesn't produce enough of certain hormones. In Addison's disease, adrenal glands, located just above the kidneys, produce too little cortisol and, often, too little aldosterone.

Signs and symptoms may include:

• Extreme fatigue
• Weight loss and decreased appetite
• Darkening of your skin (hyperpigmentation)
• Low blood pressure, even fainting
• Salt craving
• Low blood sugar (hypoglycemia)
• Nausea, diarrhea or vomiting (gastrointestinal symptoms)
• Abdominal pain
• Muscle or joint pains
• Irritability
• Depression or other behavioral symptoms
• Body hair loss or sexual dysfunction in women

All treatment for Addison's disease involves medication. You will be given hormone replacement therapy to correct the levels of steroid hormones your body isn't producing. Some options for treatment include oral corticosteroids such as:

• Hydrocortisone (Cortef), prednisone or methylprednisolone to replace cortisol. These hormones are given on a schedule to mimic the normal 24-hour fluctuation of cortisol levels.
• Fludrocortisone acetate to replace aldosterone.

You will need to get plenty of salt (sodium) in your diet, especially during heavy exercise, when the weather is hot or if you have gastrointestinal upsets, such as diarrhea.

USHING SYNDROME:Cushing’s syndrome or hypercortisolism, occurs due to abnormally high levels of the hormone cortisol. This can happen for a variety of reasons

The most common symptoms of this condition are:

• weight gain
• fatty deposits, especially in the midsection, the face (causing a round, moon-shaped face), and between the shoulders and the upper back (causing a buffalo hump)
• purple stretch marks on the breasts, arms, abdomen, and thighs
• thinning skin that bruises easily
• skin injuries that are slow to heal
• acne
• fatigue
• muscle weakness

The overall goal of Cushing’s syndrome treatment is to lower the levels of cortisol in your body. This can be accomplished in several ways. The treatment that you receive will depend on what’s causing your condition.Some medications decrease cortisol production in the adrenal glands or decrease ACTH production in the pituitary gland. Other medications block the effect of cortisol on your tissues.