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amiodarone for a patient with cardiac arrhythmia. Which factor affecting the duration of the drug should...

amiodarone for a patient with cardiac arrhythmia. Which factor affecting the duration of the drug should you consider if an adverse interaction occurs?


A. Efficacy

(B. Half-life)

C. Concentration

D. Toxic potentia
l

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Answer #1

Since amiodarone has long half-life usually 15 to 142 days and due to this its active metabolite naming desethylAmiodarone remains in the system for several weeks and is significantly responsible to develop adverse reactions as well as drug interactions and thus half life of amiodarone is the crucial factor affecting the duration of the drug, henceforth should be considered if an adverse interaction occurs.

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