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what type of antihypertensive medication that can cause cough? what is the reason?

what type of antihypertensive medication that can cause cough? what is the reason?

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Answer #1

The angiotensin-converting-enzyme inhibitor also called ACE inhibitors causes dry cough related to scratching and tickling sensation in the throat.

The ACE breaks down mediators like substance P and bradykinin, these get accumulated in the lungs when the enzyme gets inhibited. The bradykinin stimulates the prostaglandins. The increased prostaglandins and bradykinin concentration in the upper airway causes a sensation of airway sensory nerves to induce cough.

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