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Which of the following is the reason opening GABAA receptors can cause shunting inhibition? a. When...

Which of the following is the reason opening GABAA receptors can cause shunting inhibition?

a. When GABAA receptors open, they cause a decrease in membrane current

b. When GABAA receptors open, they cause an increase in membrane current

c. When GABAA receptors open, they cause a decrease in membrane resistance

d. When GABAA receptors open, they cause an increase in membrane resistance

e. none of the above

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Answer #1

Which of the following is the reason opening GABAA receptors can cause shunting inhibition?

Answer:(C) When GABAA receptors open, they cause a decrease in membrane resistance.

Neurons upon activation, brings change in membrane potential and firing rate as well as the membrane resistance. Increase in conductance is achieved by the loss in resistance, drives the non‐invasive magnetic or electric stimulation of the human brain. This is because that the larger changes in transmembrane voltage in resting neurons with low membrane conductances is brought by electrical conductance compared to the active neurons with high conductance. In shunting inhibition, the increase in membrane conductance also accompanies the classic GABAA IPSP.

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