Question

1. how you distinguish between a lynphocytosis from an infection vs one from malignancy?

2. You are examining a cancerous population of cells expressing CD 19 and CD 20 growing in an anatomically distinct pattern in a lymph node. No Reed-Sternberg cells are present. What is the most likely identity of the disease?

a. Classical Hodgkin’s Lymphoma

b. Diffuse Large B-cell Lymphoma

c. Follicular B-cell Lymphoma

d. Nodular Sclerosis Hodgkin Lymphoma

Answer 1

Answers I. Lymphocyte from an Infection of ymphocytosis is condition that offers results from your immune system working to fight off an infection or other disease, a there is an increase in white Blood cells with this Condition. cause lymphocyte from an infection cause is - viral infection - measles, mumps, monony clevis & Adenovisus & hepatitis -- influenza - tuberculoas y cytomegalo virus, Melignency infection is - Malignancy i most familiar as a cherefterization of cancer lignancy tumor contrasts with a non concerous begins tumor is that a maligneney is not self limited in its growth is capable of invading into adjacent tissue f may be capable of spreading to distant tissus. Biological of interncy factors such as age. inherited genetic defects & skin type sprisonmental exposure, fine particulate matter d risk factor, including carcinogers such as many chemicals, radioactive meterials nos factors, such as age, gender Errison risk factor, inclus occupationed & absestos, 2020 02 25 01.30

Ans. 2. The disease is Hodgkin's Lymphoma :- e the enlarge lymph nodes are usually painless, - the sweats are most comman at night (a classification of lymphoma of Hodgkins & & Lymphoma is a type of blood cancay That dovelope when lymphocyte (WBC) become out of control There are a type of classification Hodgkin lymphoma. They are named after the appearener of the lymphona cell of the cells surrounding the 1 Nodular sclerosing classical Hodgkin lymphoma - about 70 out of every 100 cases. 2, Mexed cellularity classification Hodgkin lymphomaa about 25 out of every 100 cases, g. lymphocyte- rich classical Hodgkin lymphoma - about 5 out of every 100 cases. 4. Lymphocyte - depleted classical Hodgkin Lymphony fewer than 1 in every 100 cases. (8) Diffuse Large B-cell lymphomans - Diffuse Large B-cell lymphoma is the most comman tyrse of non Hodgkin lymphoma (NHL) in the united States and world wide, accounting for about 22 7.3 of newely diagnose cases of B-cell NHL in united state. - T-cell, histiocyre-rich-B-cell lymphoma :- when riewed under a microscope this form of DLBEL look úke a few scattered large and atypical B-cell

B-cell in background of many nosmay I cal and histiocyty, which are cell that migrate from bone marrow into tissues. in Epstein-Barr virus-positive DLBCL of elderly :-) This form of DLBCL usually occurs in patrent who are age 50 or older and test positive for EBV (C) follicular B-cell lymphomait a follicular lymphoma (FL) is too slow growing type of non Hodgkin lymphoma . It develope when B-cell (also called Br nymphocytes, become abnormes. B-cell are WBC that fight infection. The abnormal. B- cell (lymphoma cells usually build up in lymph node but they can offeet othes parts of the body. (d) Nadupan sclerosis Hodgkin lymphomais Nodular sclerosis is a subtype of classical Hodgkin rymphoma Chereeterized by sclerosis, diagnostic Hodgkin & Reed - sternberg cell and other tumor cell displaying a "lacunar type morphology, The architectual pattern consist of grouped Lacunar call in lymphoid nodules swoound collagen bands. ... please read it and give thumb up...