Question

IV. Dosage Calculation by Body Mass 16. Fluorouracil 12 mg/kg/day IV, not to exceed 800 mg/day. The adult weighs 132 lbs. How many mg of the drug should the client receive per day? 17. Luminal 10 mg/kg IV. Client weighs 45 kg. How many ml should be administered if the stock is 130 mg/ml? 18. Diphenhydramine 50 mg qid. Weight = 15 lbs, Drug dosage = 20-40 mg/kg/day a) How many mL of the drug should be administered if the stock is 125 mg/5 ml? b) Is the drug dosage within the recommended range? 19. Oxacillin 40 mg/kg/day in four divided dosage. Child weighs 33 lbs. a) How many mg should the client receive per day? b) How many ml of the drug should be administered per dose if the stock is 250 mg/5 ml?

Answer 1

16.

weight of the patient = 132 lb

1 kg = 2.2 lb

Thus patient weight in kg = 132 $\div$ 2.2 = 60 kg

The ordered dose of flurouracil = 12mg/kg/day

Thus the amount of drug the client should receive  per day = 12 x 60 = 720 mg

Thus the answer is, the client should receive 720 mg / day

17.

Patients weight = 45 kg

Dose to be administered = 10 mg / kg = 45 x 10 = 450 mg

1mL stock contains 130 mg

Thus the formula is,

Volume to be administered = Desired dose/ available strength x volume available

= 450/ 130 x 1

= 3.46 mL

Thus the answer is, the amount of luminal tobe administered in mL = 3.46 mL

18.

a) Amount to be administered = 50 mg qid

Available strength of stock = 125 mg/ 5mL

Volume to be administered = Desired dose/ available strength x volume available

= 50 $\div$ 125 x 5

= 2 m L

Answer is 2 m L

b) Patient weight = 15 lb = 33 kg

Prescribed dose per day = 50 mg qid = 50 x 3 = 150 mg

Recommended drug dosage given = 20 mg - 40 mg / kg / day

20 x 33 = 660 mg / day and 40 x 33 = 1320 mg per day

The recommended dosage of drug range  = 660mg - 1320 mg / day

Thus the answer is, the drug dosage is below the recommended level.

19.  Weight of the child = 33 lbs = 15 kg ( 1kg = 2.2 lbs)

The dose of the drug per day = 40mg/kg/day

a) The amount of medication to be received per day = 40 mg x 15 kg = 600 mg/day

hence answer is 600 mg/day

b) 600 mg/day is to be administered as four divided doses

Thus amount to be administered per dose is 600mg/4 = 150mg / dose

Stock solution of the drug is 250mg/5 mL

Volume to be administered = Desired dose/ available strength x volume available

150 mg / 250 mg x 5 = 3 mL

Answer is 3 mL