Antimicrobial Review: Match the antibiotic with the mode of RESISTANCE. |
|
Antimicrobial Group |
Mechanisms of Resistance |
__ Aminoglycosides
|
A. Decreased uptake, altered target
|
Aminoglycosidase enzymatic modification , decreased uptake , altered target
fluoroquinolones efflux , altered target
β‐Lactams enzymatic destruction , altered target , decreased uptake
vanomycin Altered target, target overproduction
macrolidase enzymatic modification , decreased uptake
Antimicrobial Review: Match the antibiotic with the mode of RESISTANCE. Antimicrobial Group Mechanisms of Resistance __...
Antimicrobial Review: Match the antibiotic with the mode of ACTION. Antimicrobial Group Effect on bacteria __ Fluoroquinolones, Rifampin __ Aminoglycosides, Tetracycline __ β‐Lactams __ Polymixins __ Sulfonamides, Trimethoprim A. Inhibit cell wall synthesis B. Inhibit protein synthesis C. Disrupts metabolic processes D. Disruption of cell membrane E. Inhibit DNA synthesis
Which are the following are common mechanisms that may occur and result in resistance of bacteria to antibiotics? Check all that apply. Group of answer choices mutation that modifies antibiotic target prior exposure to biocides degradation or modification of antibiotic efflux or expulsion of antibiotic change from gram-positive to gram-negative cell wall
1) Antimicrobial X targets a specific protein in the cytoplasm of the bacterial cell, causing the bacteria to stop growing, but does not kill them. A few bacteria start to grow in the presence of antibiotic X. Analysis of the bacteria that can now grow shows that they have changed the shape of the target for antimicrobial X. What conclusion can be made? a) The change in shape of the target for antimicrobial X had no effect on the effectiveness...
Chapter 12 Study Guide 1. What are the bacterial cell targets of the different antibiotics? 2. Define the following terms: a. Antibiotic resistance b. Antibiotic sensitivity c. Broad-spectrum antibiotic d. Narrow-spectrum antibiotic e. Semisynthetic antibiotic 3. Describe the mechanism of action (target) for the following antibiotics: a. Penicillins (including semisynthetics) b. Cephalosporins c. Quinolones and Fluoroquinolones d. Bacitracin e. Vancomycin f. Carbapenems g. Tetracyclines h. Sulfonamides i. Polymyxin B j. Aminoglycosides k. Macrolides I. Chloramphenicol m. Oxazolidones n. Isoniazid o....