Antimicrobial Review: Match the antibiotic with the mode of ACTION. |
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Antimicrobial Group |
Effect on bacteria |
__ Fluoroquinolones, Rifampin |
A. Inhibit cell wall synthesis
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Antimicrobial Review: Match the antibiotic with the mode of ACTION. Antimicrobial Group Effect on bacteria __...
Antimicrobial Review: Match the antibiotic with the mode of RESISTANCE. Antimicrobial Group Mechanisms of Resistance __ Aminoglycosides __ Fluoroquinolones __ β‐Lactams __ Vancomycin __ Macrolides A. Decreased uptake, altered target B. Altered target, target overproduction C. Enzymatic destruction, altered target, decreased uptake D. Efflux, altered target E. Enzymatic modification, decreased uptake, altered target
Label the image to review major targets of drugs acting on bacterial cells. Cephalosporins Protein synthesis inhibitors acting on ribosomes Cell membrane Sulfonamides (sulfa drugs) Cell wall inhibitors Penicillins Polymyxins Erythromycin Aminoglycosides Quinolones Folic acid synthesis DNA/RNA Rifampin
Please answer all... Thank you! Options: block specific metabolic reactions (competitive analogs), deterioration of a cell membrane (perhaps concomitant with some cell wall damage), inhibit cell synthesis, inhibits DNA synthesis, interfere with protein synthesis (11 pts) 104) Identify the modes of action with the general antibiotic/chemotherapeutic categories. Only one answer is correct per agent Aminoglycosides Select One Antifungal Select One antibiotics Cephalosporins Select One Chloramphenicol Select One Erythromycin Select One Isonicotinic acid Select One hydrazide (Isoniazide) Nalidixic acid Select One...
Zithromycin inhibits protein synthesis in bacteria. However, it cannot cross gram-negative bacteria cell walls. Would you expect zithromycin to be broad or narrow spectrum? Why? Amphotericin B disrupts the plasma membrane by binding to sterols. Why can’t it be used to treat bacterial infections? Match the following processes with the statements listed below. (Answers may be used more than once.) a. transcription b. translation c. DNA replication Ciprofloxacin inhibits DNA helicase. Which process is inhibited? _______________ RCT is a nucleotide substitute for uracil. Which process is inhibited? ___________ Tetracycline...
Matching drug and mode of action 37. Penicillins and cephalosporins 38. Sulfonamides 39. Aminoglycosides 40. Amphotericin B 41. Acyclovir A) are metabolic analogs of PABA and block folic acid synthesis B) inhibits the DNA polymerase of herpesvirus C) block transpeptidases that cross-link peptidoglycan molecules D) attach to the 30S ribosomal subunit and disrupt protein synthesis in the 70S ribosome E) binds to fungal ergosterol
Name Antimicrobial Susceptibility & UV Radiation 3 Chart 1. Antimicrobial Information (Complete BEFORE LAB Session ) Describe the mode of action: (inhibition of cell wall...protein...nucleic acid...folic acid... synthesis, disruption of membrane function for the antimicrobials Nsted. Antibiotiel Code Mode of Action Other Information Antimicrobial (know this for lab exam) Bacitracin 310 Ciprofloxacin CIP5 Clindamycin CC2 Chloramphenicol C 30 Erythromycin E15 Penicillin G P 10 Polymyxin B (Colistin) PB 300 (CL 10) Rifampin RAS Streptomycin S10 Tetracycline TE30 Triple Sulfa 1559250...
Briefly explain how each of the following mechanisms of action inhibits or kills bacteria and give examples of each: Inhibition of cell wall biosynthesis Inhibition of protein synthesis Inhibition of membrane function. Inhibition of nucleic acid synthesis Inhibition of metabolic pathways Inhibition of ATP synthase
When the term parenteral is used in regards to drug administration, this applies to drugs administered _____ (choose all that apply). Select one or more: a. intravenously b. orally c. intramuscularly d. topically Protein synthesis occurs in all living cells. Why, then, are some antimicrobial drugs that target protein synthesis selectively toxic to bacteria? Select one: a. The protein synthesis in human cells occurs less frequently than that in bacterial cells. b. The ribosomes found in human cells and those...
Antibiotic A: 0.5 kDa protein, targets peptidoglycan Antibiotic B: 20 kDa protein, targets peptidoglycan Antibiotic C: Cationic Antimicrobial Peptide (CAMP) Antibiotic D: Targets lipopolysaccharide With some more searching, you found the following results in your notebook. Percent Survival Percent Survival Antibiotic Antibiotic Control Control protoplast C. difficile protoplast Bacteria S. aureus E. coli V. cholera C. difficile S. aureus E. coli V. cholera Bacteria Percent Survival Percent Survival Antibiotic Antibiotic Control Control E.coli S. aureus Bacteria S. aureus E. colis...
1. Which drug category includes the penicillins? Group of answer choices Cell wall synthesis inhibitors Protein synthesis inhibitors Metabolism inhibitors DNA synthesis inhibitors 2. You are assisting in the care of a client taking gentamicin (Cidomycin). What lab value would be most important to monitor for this drug? Group of answer choices Lab value showing kidney function Lab value showing potassium level Lab value showing cholesterol level Lab value showing clotting time 3. What does the term “virulence” mean? Group...