Question

Name Antimicrobial Susceptibility & UV Radiation 3 Chart 1. Antimicrobial Information (Complete BEFORE LAB Session ) Describe the mode of action: (inhibition of cell wall...protein...nucleic acid...folic acid... synthesis, disruption of membrane function for the antimicrobials Nsted. Antibiotiel Code Mode of Action Other Information Antimicrobial (know this for lab exam) Bacitracin 310 Ciprofloxacin CIP5 Clindamycin CC2 Chloramphenicol C 30 Erythromycin E15 Penicillin G P 10 Polymyxin B (Colistin) PB 300 (CL 10) Rifampin RAS Streptomycin S10 Tetracycline TE30 Triple Sulfa 1559250

Answer 1

kay Companion Bacitracin : MODE OF ACTION Bacticidal to Gram positive bacteria & Having little activity for gram negative bacteria " Bactopreno a transport protun that caries peptidoglycos components towards outside of the membrane On cell membrane bautracin prevents phasphorylation of bactopreno - Hence ist inhibts peptidoglycan synthesis in bacterial cell wall synthesis in skin infection corticosteroid to OTHER INFORMATION" Used Also contain antinflammatory reduce inflammation a Bacitracin produced by - Bacelles subtiles Ciprofloxacinto mode of action. It topoisomerase [ required by which bacterial inhibits DNA gyrase y type I 40 to seprate DNA in cell division] growth inhibet. Other Information. negative bacteria They less mainly active active for for gram & gram positive Clindamycin ode of They inhibits Action synthesis bacterial proteen ribosomal inhibiting translocation CS Othere on formation om Eartscanner higher Mafinly concentration Bacteriostatic , Bacteridal

chloramphenicol full companion mode of Action It prevents protien Chain elongation by inhibiting peptidyl transferase of the bacterial to ribosome! residues They bruds of small subunit 23 S ORNA U of sos ribosome and prevent bonding in peptides: other. They are bacteriostatic. - Now it is banned because it causes aplastic anemia - Erythromycin & Mode of Action & They bends to bacterial sos ribosomal subunits - that inhibits peptidyl transferase activity and interferes with translocation of amino acide deurug protelu synthesis Other : Erythromycin are macrolide antibiotic - Syntheofzed by & Streptomyces erythrees y Penickellin - G - mode they inhibets Other : of action. In bacterial cell transpeptidase & catalayse Active against grow auso graue negative wall synthesis synthesis They Polymxin - B - Mode of action Acts like detergent. Interacts with lipopolysaccharide of the outou membrane of grame negative bacter a other & Rapid bactericidal agent Rifampina Rifamp on They Puhibets bacterial DNA- dependent Punebiting by Punebiting DNA dependent RNA T ZNĀ can synthesis DNA dependent RNA polymerese darheiceanne RNA Gynthen's ' Terange option fubibited

Date Page - mycompanion Other Used in tuberculosis Rifampin causes red urin - Streptomy cene mode of action ; It binds ng misreading or synthesis Unable to 3of ribosomal t- RNA hence subunit protelu - other e Irreversibly bluding 3os. - Aminogly coside . Tetracyclen o Mode of Action & They beads to 30s ribosome of bacteria and hence prevents to attachment with aminoayl t-RNA to RNA ribosome complex other o Bautento state causes Nosea, youffiner diarrhea, loss of appetite Triple tulfer MOA Sulfa duugs binds to dete dikey droptervate syuthase enzyme . This enzyme is essential for bctered for folate synthesis Other effectively treat bacterial infection as haemorrhagic septicemia, cotton mouth disease o suscepti belity records undlec autobiotics a - and to detect ogen & to to determine which perticular bacteria possible string resistance assure sucep tebelity to pathogen in drug Common ----.e-with anner-

fare companion resistance.. antibiotic au confer resistance R- plasmid e They stands for factor o Genes present on R- plasmid to be autibiotics. as tra genes are responsible plasmid grove cell to cell to spread of MRSA 8 Methicellon resistance staphylococcus aureus is a bacterium causes infection la different parts . They are rasistant to common antibiotics " There infection is fatal URE Vancomy uu - resitant Enterococcus. Scann sperante person to person through derect contact CamScanner