Question

Question 25 Mrs. Field has contracted a fungal infection after being on a mission trip in a third world county label shown below, determine how many ml of caspofungin you will administer per dose if the one on a mission trip in a third world country. Using the drug Cancidas 70 mg IV x 1 on day one and 50 mg daily x 6 days. Cancidas (caspofungin acetate) For Injection RX only 50 mg* For Intravenous Use Only MERCK & CO.NC. Store Refrigerated. "Vial contains 54.6 mg of caspofungin. Reconstitute with 10.8 ml of diluent to obtain final concentration of 5 mg/mL. FOR INSTRUCTIONS ON RECONSTITUTION AND DILUTION AND DOSAGE, SEE PACKAGE INSERT. No. 3822 NDC 0006-3822-10 9343704 Lot & Exp. a) Initial dose: 12 ml, subsequent doses: 10 ml b) Initial dose: 10 ml, subsequent doses: 14 ml c) Initial dose: 10 ml, subsequent doses: 10 ml d) Initial dose: 14 ml, subsequent doses: 10 ml

Answer 1

order dose 70 MG IV in first day then 50 mg daily for 6 days.

Add 10.8 ml of dilutant to obtain 5 mg per ml (According to the label)

so, for initial dose on the first day

70mg = 5mg/ml = 14m/

For subsequent doses

50mg - 5mg/ml = 10ml

Answer - d. Initial dose: 14 ml, subsequent doses: 10 ml