Question

A patient who is taking adalimumab (Humira) develops a sore throat, bruising and fatigue. The nurse...

A patient who is taking adalimumab (Humira) develops a sore throat, bruising and fatigue. The nurse will further assess for drug induced:
Hypersensitivity or allergy
Stevens-Johnson syndrome
Low white blood cell count
Idiopathic reaction

Which is the correct one and why?

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Answer #1
  • Patient taking Adalimumab developed sore throat , bruising and fatigue due to Adalimumab induced stevens-johnson syndrome.
  • Stevens-johnson syndrome is a rare skin reaction which is usually occurs due to a medication and symptoms like sore throat, and fatigue will develop several weeks before the skin reactions starts.
  • Cutaneous skin reactions are comonger half lifemon in anti-TNF alpha drugs like adalimumab
  • Adalimumab is having l and stevens johnson syndrome is seen with in 4-8 weeks of the therapy.
  • It is a immune-mediated skin reaction due to the inhibition of tumor necrosis factor alpha which is responsible for apoptosis.
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