Question

5. Appraise heuea Lymphatic Disease Case Study Ms. Y. is a 31-year-old female who reported to her physician that she has recently lost weight, always seems tired, and has experienced night sweats. A few months ago she had noticed a small firm lump on her neck that was painless and not tender, so she ignored it. Closer physical examination revealed swelling of several lymph nodes in the neck and throat region. A blood test indicated a decreased lymphocyte count and a lymph node biopsy revealed the presence of Reed-Sternberg cells, confirming the diagnosis of Hodgkin's lymphoma. Due Friday Discussion Questions 1. Relate the pathophysiologic changes to the manifestations and lab results 2. Differentiate the four stages of the disease based on the Ann Arbor staging system and appraise the patient's probably stage. Interpret the prognosis 3. Examine the treatment options for this patient 4. Distinguish the differences between Hodgkin's and Non-Hodgkin's Lymphomas. Dropbox 3 Rubric Hematology Case Study Drnficiant IInarrantahlo Criterisa Arrentahle Print Download Reflect in ePortfolico 5/17/20 https://ccis.ucourses.com/d2/le/content/837634/viewContent/4107929/View

Answer 1

Hematology case study :

Q. No. 1. Answer :

Pathophysiology of pernicious anemia :

Due to destruction of body immune system, there is a loss of parietal cells, or loss of stomach cells which will produces the intrinsic factor, which is useful for absorption of vitamin B12.

So that there is vitamin deficiency leads to development of pernicious anemia.

Q. No. 2. Answer :

Atrophic gastritis, chrohns diseases, celiac disease bacterial growth, immune system disorder such as graves diseases these are the intestinal disorders may leads to stomach lining has been thinned, which is useful for absorption of vitamin B12 and iron, due to that decreased intrinsic factor, may leads to poor absorption of iron and vitamin B12.

Q. No. 3. Answer :

* pernicious anemia due to vitamin B12 deficiency, the complications like vision problems, neurological problems like memory loss, parasthesia ect.

* here we are seeing tingling on his toes, nausea and occasionally diarrhea, these are the symptoms we may seen in pernicious anemia also.

Q. No. 4. Answer :

* Full blood count or complete blood picture,

* homocrystine and methyl malonic acid levels should be done, if it increases it indicates vit b12 deficiency,

* intrinsic factor blocking antibody blood test should be done.

* and parietal cells antibody tests should be perform.