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why should Mylanta and Rantidine not be taken together?

why should Mylanta and Rantidine not be taken together?

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When both anatacids and H2 blockers are used together, the further reduction of gastric acid may allow for bacteria to multiply in the digestive system and the risk of infection may be increased. Oral antacids and some aluminum, calcium, and magnesium salts may decrease oral H2 blocker plasma concentrations. The mechanism may be related to reduced gastric absorption and bioavailability due to acid-neutralizing effects. It is recommended that H2 blocker be administered one to two hours before one of these preparations

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