Question

PN 200 Fundamentals of Nursing II Osteoarthritis - Naprosyn An older aduit patient has osteoarthritis. The patient had previously taken aspirin for the condition and later was prescribed naproxen (Naprosyn). Both drugs caused GI distress. The health care provider discontinued the naproxen and prescribed celecoxib (Celebrex) 100 mg twice a day 1. How does celecoxib differ from naproxen? Describe the advantages and disadvantages of taking celecoxib for ostecarthitis. What is the rationale in checking the patient's renal and liver function before prescribing celecoxis being sure to include your rationale for your answer? 3. 4. What should be included in the mursing assessment in regard to the patient's physical and irng histories? The patien: states that the arhritie pain is not relieved with the new drug. The patient wants to cake the celecoxib with the naproxen. Explain the efects of these two medications when taken together. 5. 5. What would be your best response to the patient's request being sure to include the rationale for your answer? 7. Develop a teaching plan for the patient that inoludes medication use and nursing measures to relieve pain, Reviewed 12/18

Answer 1

1.The main differences between Celecoxib and Naproxen are

Naproxen	Celecoxib
Available without prescription	Available only with prescription
Interferes with blood clotting	Doesn't interfere with blood clotting
can treat mild to moderate pain	Can treat any severe form of pain especiallyrelated to joints nd bones
High levelnof stomach ulcer	Less inflammatory process and stomach ulcer

2.Advantages

• Reduces swelling and pain
• Protects the lining of the stomach thereby decreasing the chance of stomach ulcer

Disadvantages

• To be taken at least for 2 weeks to get the full effect
• Flatulence and insomnia are typical side effects
• Overdose may be fatal

3.The celecoxib drug is metabolized in liver and eliminated via kidney .It can affect the function of kidney and lead to kidney failure and hepatotoxicity.Hence before initiating this medication the history of kidney and liver disease along with reports to be assessed.

4.The patient has to be checked for taking medication like aspirin, other NSAIDS because taking both can lead to severe gastrointestinal problems like peptic or intestinal ulcers,bleeding .Blood thinners interact with this drug .It may incraese the blood pressure further even if the payient is on antihypertensive treatment. The patients weight has yo be considered while calculating the dose

The patient has to be informed both medication are not prescribed at a time because of serious side effects like bleeding ,inflammation, intestinal ulcers.Celecoxib is more effective with reduced side effects th a Naproxen